Seroprevalence of herpes simplex 2 Infection in patients attending STI clinic
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 8
Abstract
Background: HSV-2 is the primary cause of genital herpes. About 95% of genital infections due to HSV are predominantly caused by HSV-2.Serology is especially useful in recurrent, atypical lesions, culture negative cases and unrecognized infections. Laboratory confirmation of the diagnosis in patients who present with genital ulceration is mandatory. The present study was undertaken to determine the prevalence of HSV-2 antibodies among the patients attending STI clinic. Material and Methods: The study included clinically suspected 100 cases of genital herpes attending STI OPD at our institute. Serum samples were obtained from all the patients after written consent. A portion of serum sample was used for the detection of HSV-2 IgM antibody by HSV-2 IgM kits [DIA.PRO Diagnostic Bioprobe SRL,Italy]. Results: Out of 100 patients 36% were HSV-2 IgM ELISA positive and 64% were negative. Maximum (61%) ELISA positive cases were in the 21-30 years of age group. Male preponderance was apparently seen with 24 being males and 12 were females out of 36 HSV-2 seropositive cases. Conclusion: The seroprevalence of HSV-2 by IgM ELISA Test was 36%.The use of serological testing for diagnosis of genital ulcerative lesions is of course an indirect method, but it is useful in the situation where HSV is the most likely diagnosis of genital lesion and that the other causes of genital ulcerations are infrequent and have been ruled out.
Authors and Affiliations
Shubhangi Vikram Tambare, Balaji Kondabarao Mane, J B Bhakre, A S Damle
Keywords
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