Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in tertiary care centre of central India
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 8, Issue 3
Abstract
Background: Screening of transfusion transmissible infections among blood donors can be a cost effective approach to monitor the prevalence, distribution and trends of infections among healthy looking individuals. Aims: The present study was conducted to determine the seroprevalence of HIV, HBSAg, HCV & syphilis among blood donors of Tertiary Care Centre of Central India. Retrospective study of four years from Jan. 2014 to Dec. 2017 was done. Material and Methods: A total of 8,172 were screened samples in blood bank, among them163 were found to be positive for infections like HIV, HBS Ag, HCV & syphilis among. Blood samples were tested for the presence of HIV 1 & 2 antibodies, HBS Ag, HCVAb using commercial ELISA kits following standard protocols & syphilis was screened by Rapid Plasma Reagin type. Results: Seroprevalence of HIV, HBV (HBSAg) and HCV were observed to be HBSAg (1.04%), HCV (0.49%), HIV (0.37%) & Syphilis (0.01%) in our study among the blood donors. Transfusion Transmitted Infections were prevalent among male blood donors and in replacement donors. Conclusion: The seroprevalence of transfusion transmitted diseases in the study is very low in voluntary donors as compared to replacement donors. There was a declining trend of seroprevalence for HBSAg & HCV infection which indicates that the selection of donors is of high quality which was achieved by creation of awareness by education of prospective donor populations.
Authors and Affiliations
Anita Sardeshpande, Sanjay Parate
Keywords
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- DOI 10.26611/105833
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