Seroprevalence of Human Cytomegalovirus and Rubella Virus Antibodies among Anti-retroviral Naive HIV Patients in Lagos
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2014, Vol 4, Issue 9
Abstract
Background/Aims: Opportunistic infections such as Cytomegalovirus (CMV) and Rubella virus that pose no threat to healthy individuals can be life threatening in those with impaired immune systems. The aim of this study was to determine the sero-prevalence of human Cytomegalovirus (CMV) and Rubella Immunoglobulin M and G (IgM and IgG) antibodies among anti-retroviral naive patients in Lagos. Study Design: This is a cross sectional study. Place and Duration of Study: AIDS Prevention Initiative in Nigeria (APIN) clinic in Lagos University Teaching Hospital (LUTH) between April 2011 and May 2012. Methodology: The study was carried out among 80 (28 males and 52 females) HIV infected adults attending the AIDS Prevention Initiative in Nigeria (APIN) clinic in Lagos University Teaching Hospital and the patients were aged between 18 and 60 years. IgG and IgM assay were performed using ELISA reagents (produced by Biotec laboratories, United Kingdom). Also, CD4+ cell counts were evaluated. Pearson’s Chi-squared test was used for the analytic assessment. Results: From our findings, twenty (25%) patients were positive for CMV IgM and sixty (75%) patients were positive for CMV IgG. Also, 59 (73.75%) patients were positive for Rubella IgG and only one (1.25%) patient was positive for rubella IgM. There was no significant statistical difference in seroprevalences of CMV-IgM, CMV- IgG, and rubella IgG with respect to sex, age, and CD4+ cell counts. Conclusion: This study showed that the sero-prevalence of CMV and Rubella virus is high among anti-retroviral naive HIV patients in Lagos, Nigeria.
Authors and Affiliations
O. Akintunde Olajumoke, I. Ayolabi Christianah, I. Opara Morrison, A. Akanmu Sulaimon, S. Bamiro Babajide, A. Adeleye Isaac, O. Adeoye Grace, T. Seriki Abiodun
Keywords
Related Articles
- EP ID EP343412
- DOI 10.9734/IJTDH/2014/10465
- Views 57
- Downloads 0
An Eight-Year Review of Morbidity and Mortality among Adult Patients with Tetanus at a Tertiary Hospital in Zaria, Northern Nigeria
Background: Tetanus infection is a major cause of morbidity and mortality in many developing countries. The infection results from contamination of wound by Clostridium tetani in unimmunized individuals. The morbidity is...
Radiological Features of Right Destroyed Lungs Syndrome with Pathologic Dextrocardia
Chronic lungs disease such as relapsed tuberculosis of the lungs could lead to complications that could alter the gross anatomy of a region of the body. Many complications have been reported due to chronic and relapsed l...
Investigation of an Outbreak of Acute Methanol Poisoning in a Southwest State of Nigeria
Aims: An outbreak of sudden deaths with clinical features suggestive of acute methanol poisoning was reported. An epidemiological investigation was conducted to verify the diagnosis and identify risk factors. Methodolog...
Pattern of Neonatal Mortality in a Teritiary Health Facility in Umuahia, South East, Nigeria
Background: Neonatal mortality rates are highest in Sub-Saharan Africa, with Nigeria inclusive. And so the aim of the current study was to audit the pattern of neonatal deaths. Study Design: A cross sectional retrospecti...
Evaluation of Janani Suraksha Yojana (JSY) in Maharashtra, India: Important Lessons for Implementation
Aims: The study was conducted to estimate the proportion of eligible women for Janani Suraksha Yojana and to understand the factors affecting receipt of benefits in Maharashtra State, India. Methodology: It was as compa...