Seroprevalence of Rheumatoid Factor in Tertiary Care Hospital
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 6
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that affects many tissues and organs but mainly affects the joints, producing a proliferative and inflammatory disease that progresses to damage the joint cartilage and ankylosis of the joints. About 1% of the world’s population is affected by RA. Women three to five times more often than men along with it is more common in the age group of 40 to 70 years of age. The useful serological markers for RA are Rheumatoid factor (RF) and antibodies to citrullinated peptides. This present study was done to find out the prevalence of serological markers in suspected arthritis cases in tertiary care hospitals. This prospective study was carried out in the serology section in the central pathology lab in Government Medical College, Banda from April 2015 to August 2018. A total of 776 blood samples were received for RA factor analysis. Out of 776 samples, 111 samples were positive for RA factor of 14.3% prevalence. A total of 88 cases were females and 23 were males. The most common age group involved was 21–60 years in females and 40–70 years in males. For the evaluation of patients with suspected RA, it is recommended to perform anti-cyclic citrullinated peptide antibody and RF analysis to increase the specificity of the results.
Authors and Affiliations
Varad Vardhan Bisen
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