Seroprevalence of Syphilis among ANC and STD clinic attendees in a Tertiary Care Hospital in South India.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Syphilis is a sexually transmitted disease (STD), caused by Treponema pallidum subsp. pallidum. Syphilis affects nearly 1.36 million pregnant women, majority of these cases being concentrated in the developing countries. This hospital based retrospective study was conducted to understand the syphilis prevalence among ANC cases and STD clinic attendees in a tertiary care teaching hospital in south India. The data was collected by retrospective analysis of laboratory records over a period of one year from January 2017 to December 2017. Blood samples received from pregnant women attending antenatal clinics and STD clinic attendees were taken up for the study. All the serum samples were subjected to qualitative Rapid Plasma Reagin (RPR) test using standard procedures and the reactive samples were further tested by quantitative RPR and Treponema Pallidum Haemagglutination. Samples which were reactive by both qualitative RPR and TPHA were considered as seropositive for Syphilis. Out of the 6864 samples tested 145 were reactive for Syphilis by both quantitative RPR and TPHA. The overall seroprevalence in this study was found to be 2.1%. Syphilis seroprevalence among the ANC cases and STD clinic attendees were found to be 0.39% and 2.95% respectively. The higher seroprevalence was noted among the sexually active age groups (15-40 yrs). The seroprevalence of Syphilis was low among ANC cases when compared to STD clinic attendees. Among the STD clinic attendees males showed higher seroprevalence indicating high risk behavior (MSM) and unsafe sexual practices. Syphilis prevalence among high risk groups could be reduced by behavior modification, promoting safe sexual practices, enhanced case detection, treatment and follow up.
Authors and Affiliations
Mythily N, Ashokkumar C, Bharathi Santhose N
Keywords
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- EP ID EP375199
- DOI 10.9790/0853-1705107880.
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