Seroprevalence of TORCH Infections in Women with Bad Obstetric History in North West Region of Rajasthan
Journal Title: Saudi Journal of Medicine - Year 2018, Vol 3, Issue 7
Abstract
Bad obstetric history(BOH) is specific to women specially during childbearing age, causes by TORCH group (Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), Herpes simplex virus) and others agents like Chlamydia trachomatis, Treponema pallidum, Neisseria gonorrhoeae, HIV,etc The objective of the study is to evaluate the incidence of TORCH infections in pregnancy wastage in women with bad obstetric history (BOH).The study included 200 women aging from 15 to over than 46years with bad obstetric history and 75 clinically normal women with previous normal full term deliveries. Serological evaluation for TORCH infections was carried out by IgM ELISA method. Seropositivity for toxoplasma was 27.33%, rubella 21.66%, cytomegalovirus 34.33% and herpes simplex virus 17.66 with high frequency of stillbirths 94.11 %, Maximum number of cases of abortion (27.27%), intrauterine growth retardation (9.37%), intrauterine death (17.64%) and preterm labor (18.18%) was associated with toxoplasma infection. Seropositivity in women with BOH is demonstrates a strong association between the infectious agents (Toxoplasma, Rubella and CMV)) A previous history of pregnancy wastage and the serological reaction for TORCH infections during current pregnancy must be considered while managing BOH cases so as to reduce the adverse fetal outcome.
Authors and Affiliations
Miss Madhavi Vyas, Dr. Rahul Acharya
Keywords
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