Seroprevalence of Transfusion Transmitted Infection (TTI) among Healthy Blood Donor and Their Distribution within Blood Groups - A Study from Kolkata
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1
Abstract
Introduction: Blood transfusion is an integral and life saving procedure of modern medicine, but simultaneously it carries the risk of transmitting the life- threatening transfusion-transmissible infectious agents such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and malaria. Thus ensuring the safety of blood is a major concern in transfusion therapy although the improved screening and testing of blood donors has significantly reduced transfusiontransmitted diseases The aim of the study was to find out the prevalence of transfusion transmitted infections (TTI) in voluntary donors. Materials & Methods: A total of 14646 voluntary donors were analysed for the prevalence of TTI over a period of 1 year. HBV, HCV and HIV were tested by ELISA methods malaria also screened with rapid card test with pinciple of immunochrmatography. syphilis was screened with the principle of rapid plasma reagin test Results: Prevalence of TTI in total donors was 3.56 % as whole, whereas in Rh negative donors it is only 1 %. Prevalence of Hepatitis B was highest (1.38) followed by Hepatitis-C (1.31), HIV (0.4), VDRL (0.32) and malaria (0.12). Distribution pattern of TTI fallows identically with the blood group distribution in Rh positive population but does not fallow in Rh negative blood group population. Conclusion: TTI remains a important problem in blood transfusion. Proper protocol should be applied in selecting and screening donors to safeguard the health of people receiving blood transfusions
Authors and Affiliations
Dr Kusumita Mandal
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