SERUM BILIRUBIN RELIABLE DIAGNOSTIC MARKER IN DETECTING COMPLICATED APPENDICITIS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2016, Vol 3, Issue 2
Abstract
BACKGROUND The aims of the study were: 1) To establish hyperbilirubinemia as a Reliable marker in gangrenous/perforated appendicitis; and 2) To compare other variables such as white blood cell count and Alvarado score in a similar manner. METHODS This is a prospective cohort single centred study done on 100 patients of acute appendicitis admitted to our hospital through emergency and surgical OPD. Clinical examination, laboratory and radiological investigations were done to establish the diagnosis. Alvarado score was performed in every case to assess the severity of the disease pre-operatively. All the postoperative specimens ware subjected to histo-pathological examination for confirmation of the diagnosis. The clinical and laboratory data was compiled and analysed. Statistical analysis was performed using SPSS program for Windows version 21.0. P value <0.05 was considered as significant. RESULTS Marked raise of Total serum bilirubin was found in Gangrenous and impending perforated appendix. Even though TLC was raised, it was not consistent in all cases of gangrene or perforated appendicitis. The P value of TLC was 0.016 and the P value of total serum bilirubin was 0.000, which is definitely significant. CONCLUSION Serum bilirubin is a reliable diagnostic marker in acute appendicitis particularly in gangrenous/perforated appendicitis.
Authors and Affiliations
Subramanyam V. V, Gidion Bangla, Jyothi C
Keywords
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- EP ID EP231580
- DOI 10.18410/jebmh/2016/15
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