Serum C-Reactive Protien (CRP) - A Dependent Prognostic Marker in Pulmonary Tuberculosis
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 10
Abstract
the world and accounts for nearly 1/4th of the global burden of TB. So study aimed to assess the values of Serum C - reactive protein (CRP) in cases of Pulmonary Tuberculosis (TB) and to evaluate its utility as a serological marker for de novo, treated cases and cases undergoing treatment for Pulmonary TB. Material and methods: This was a Tertiary hospital based Prospective study of 2 months duration. All patients of pulmonary TB (known as well as newly detected cases) who visited the Respiratory Medicine OPD of this hospital were included in this study. Results: Of the 50 patients of tuberculosis we assessed, we found 52% newly detected cases of pulmonary TB, 18% undergoing anti-tubercular treatment, 10% Cured cases, 16% treatment defaulters and 4% treatment resistant. The CRP level in the newly detected TB patients was found to be 51.22 ±30.54. Those undergoing anti-tubercular treatment had a mean CRP value of 43.29±28.94 and it dropped as the course of treatment progressed. CRP in patients who had started treatment was 66.55±17.22 and those who had completed their treatment were 23.87±26.05. The patients who had almost completed the treatment had a mean CRP level of 4.78±4.34. Defaulters had a mean CRP of 66.90±22.66 and the treatment failure had a mean CRP of 87.37±5.83. Conclusion: CRP levels are raised in tuberculosis and fall and attain normal values by the end of treatment. If the values are consistently high despite treatment, then there is either resistance to drugs or the patient is not complying with the treatment (Defaulter).
Authors and Affiliations
Parijat Pansey, Samarth Shukla, Sourya Acharya
Keywords
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