Serum Calcium and Alkaline Phosphatase Level among Pre-Menopausal and Post-Menopausal Women in Rupandehi District of Nepal: A Co-Relational Study

Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 8

Abstract

Bone turnover markers and its consequence to poor health outcomes among post- menopausal women have been well understood elsewhere, but it is not well researched in Nepal. Objective: This study is aimed to assess the association of bone turnover markers in pre- and post-menopausal women in Rupandehi district of Nepal. Methods: A cross-sectional study was conducted during August 2014 to September 2016 in a total of 400 study participants with an equal number of pre- and post-menopausal women (200 each of the test and control group). Blood samples for both pre-menopausal and post-menopausal women were collected and analysed for the selected bone turnover markers. Descriptive statistics, bivariate and correlation statistics were employed for the study. Data were analysed using SPSS software version 20. Results: This study identified that low serum calcium level. [(Post-menopausal; mean 8.53, SD 0.619 vs. pre menopausal; mean 9.23, SD 0.793) (P=0.000)] and high alkaline phosphatase (ALP) level in postmenopausal women compared to its counterparts [post-menopausal group 106.76 (SD 40.85) compared to the pre-menopausal group 85.20 (SD 31.262)]. There was a significant negative correlation between serum calcium and alkaline phosphatase. Conclusion: As the result of this study showed a significant decrease in serum calcium and increase in serum ALP among normal postmenopausal women suggesting an elevated bone turnover may result into bone mass reduction, hormonal therapy to prevent bone mass reduction to concerned population may be suggested. Further, studies covering many bone markers in a large population are recommended.

Authors and Affiliations

Bikram Khadka

Keywords

Related Articles

A Study to Assess the Effectiveness of Breathing Exercises on the Quality of Sleep among Patients with Dyspnoea in a Selected Hospital, Bangalore

Background: The term dyspnoea is breathlessness or shortness of breath, laboured or difficult breathing. It is a sign of a variety of disorders and is primarily an indication of inadequate ventilation or of insufficient...

Exploring the Behavioural Attitude of the Employees in the Public Health Care System in the State of Kerala

Healthcare sector is one the major sector in a country and the majority of the Indian populations rely on the public health care sector of the country. The Government hospitals in the states of the country have the best...

Effects of Intensive Coordination Training While Walking In Parallel Bars with Visual Feedback in a Case of Spinocerebellar Ataxia Type I: A Case Report

Background: This study attempts to explore the effect of 3 months long intensive bi-manual coordination training, through visual and auditory bio-feedback, along with concurrent gait training on parallel bars, on the sym...

Phantom Hernia Due to Abdominal Herpes Zoster

Most of the complications of herpes zoster are sensory. Segmental motor weakness is an unusual complication. We present a case of 50 years old male who presented with phantom hernia 3 weeks after the appearance of herpes...

Physical Activity, Sedentary Behaviors and Dietary Habits among Adults Living in Riyadh City, Kingdom of Saudi Arabia

Study Objective: The purpose of this cross-sectional study was to explore the differences in weight status, obesity and patterns of physical activity (PA), sedentary behaviors (SB) and dietary habits (DH) in relation to...

Download PDF file
  • EP ID EP373587
  • DOI -
  • Views 69
  • Downloads 0

How To Cite

Bikram Khadka (2017). Serum Calcium and Alkaline Phosphatase Level among Pre-Menopausal and Post-Menopausal Women in Rupandehi District of Nepal: A Co-Relational Study. International Journal of Health Sciences and Research, 7(8), 136-141. https://europub.co.uk/articles/-A-373587