Serum Chromium is Inversely Correlated with the Carotid Intimaâ Media Thickness in Type 2 Diabetic Subjects
Journal Title: Iranian journal of diabetes and obesity (IJDO) - Year 2023, Vol 15, Issue 3
Abstract
Objective: The aim of this study was to determine and correlate the serum chromium in Carotid intima - media thickness (CIMT) in type 2 Diabetes Mellitus (T2DM) subjects. Materials and Methods: The present case – control study included 40 healthy controls and 45 T2DM subjects that were selected through non-probability (purposive) sampling by prior inclusion and exclusion criteria. Serum chromium (Cr) was detected and measured on inductively coupled “Plasma Optical Emission Spectrophotometer” (ICP- OES)- Carotid artery was examined with a 7.5-MHz linear-array transducer (Siemens Acuson x300) sonography. Data was analyzed by Student’s t test and Chi square test in the SPSS 22.0 (USA). Linear regression model was used for predicting carotid intima media thickness. Level of confidence interval of statistical significance was 95% (P≤ 0.05). Results: Serum Cr in controls and cases was noted 0.873 (± 0.162) and 0.281 (± 0.240) µg/ml (P= 0.001). Serum Cr proved negative correlation with random blood sugar (r= -0.145, P= 0.185), HbA1c (r= -0.145, P= 0.0001) and CIMT (r= -0.730, P= 0.0001). Multiple regression analysis model showed significant association of serum Cr (r= -0.730, P< 0.0001) and HbA1c (r= 0.754, P< 0.0001) with the CIMT. Conclusion: The present study reported serum Cr was inversely correlated with the carotid intima - media thickness that is a marker of atherosclerosis. Cr supplements may be advised to diabetics in clinical management.
Authors and Affiliations
Fatima Qureshi,Haji Khan Khoharo,
Keywords
Related Articles
- EP ID EP721460
- DOI -
- Views 29
- Downloads 0
Investigating the rs2237892 and rs231362 Polymorphisms of KCNQ1 Gene Associations with Type 2 Diabetes in an Iranian Population (Yazd Province)
Objective: Type 2 diabetes (T2DM) is a worldwide prevalent metabolic disorder and the cause of many morbidities and mortalities. KCNQ1 gene encodes α-subunit of voltage-gated potassium (K+) channel which plays a role in...
The First Phase Registration of Type 1 Diabetes in Yazd, Iran
Objective: The aim of this study was registration of type 1 diabetes mellitus (T1DM) in Yazd (the first phase of registration). Materials and Methods: This study was a cross-sectional study on the first phase registrati...
The Impact of HIIT on the cTnT Response in Sedentary Obese Young Men
Objective: Evaluation of the effect of 8 weeks of High-Intensity Interval Training (HIIT) on the serum level of cardiac troponin T (cTnT) in sedentary obese young men. Materials and Methods: Thirty sedentary men were ra...
The Effect of High-Intensity Interval Training on Apoptotic-Related Genes in Skeletal Muscle and Serumic TNF-Alpha of Diabetic Rats
Objective: Diabetes is characterized by a comprehensive increase in apoptosis, mitochondrial dysfunction, and inflammation in skeletal muscle. Impaired mitochondrial function in skeletal muscle leads to an increase in Cy...
The Effect of Combined Exercises and Consumption of Mulberry Leaf Extract on Serum Inflammatory Markers Level in Elderly Type 2 Diabetes Mellitus Men
Objective: This study aimed to investigate the effect of 8 weeks combined exercise and consumption of Mulberry leaf extract on the serum levels of inflammatory and atherosclerosis indicators in elderly men with type 2 di...