SERUM INFLAMMATORY MARKERS OF DIABETIC KIDNEY DISEASE AND THEIR CORRELATION TO LIPID PARAMETERS AMONG DIABETIC INDIVIDUALS OF EASTERN INDIA
Journal Title: IJSR-International Journal Of Scientific Research - Year 2019, Vol 8, Issue 1
Abstract
Background : Diabetes mellitus is the leading cause of chronic renal failure . As the period of diabetes progresses there is simultaneous increase of inflammatory markers like high sensitive C reactive protein (hsCRP) with degree of renal involvement, suggested by albumin creatinine ratio and also dyslipidemia in diabetic patients. Materials & Methods: 120 diabetic individuals aged (30-60) yrs, divided in 3 groups of 40 subjects in each, namely: a) newly diagnosed˂5 years b) 5-10 years after diagnosis and c) ≥10 years after diagnosis were recruited as study subjects from a tertiary care hospital in sub Himalayan region. Results : Descriptive studies showing mean values of hsCRP ,ACR & lipid parameters were done in all 3 groups. One-way ANOVA with post hoc analysis after Bonferroni correction in 3 different groups enunciated a significant and statistical increase (p <.001) of both hsCRP &ACR with duration of diabetes unlike the lipid parameters. hsCRP, ACR, cholesterol & LDL even illustrated a very significant correlation between each other (p<0.001) , TG to hsCRP while HDL showed no correlation to any parameters. Conclusion: Early detection, monitoring of inflammatory markers hsCRP, ACR & deranged lipid parameters are predictors of diabetic nephropathy that can help in modulating diabetes and its complications.
Authors and Affiliations
Dona Acharjya, Ushasi Banerjee, Swati Bhattacharyya
Keywords
Related Articles
- EP ID EP463509
- DOI -
- Views 58
- Downloads 0
RAPID ANTIGEN TESTING FOR STREP SORE THROAT
This was a cross sectional study to estimate the prevalence of Group A Streptococcal (GAS) infection among children with acute sore throat and to compare results of Rapid antigen detection test (RADT) with throat culture...
A COMPARATIVE STUDY REGARDING THE DIFFERENCE IN ATTITUDE OF INTERNS TOWARDS PSYCHIATRIC ILLNESS AND CHRONIC MEDICAL ILLNESS
Attitude of doctors towards a specific illness play major role in the care of patients. Internship, the final stage in MBBS training is important in developing attitudes towards different diseases. Psychiatric illnesses...
Awareness of Fixed Dose Combinations in Medical Undergraduate Students: A Question Based Study
is study was conducted among the medical students to evaluate the awareness of fixed dose combinations (FDCs). is study was conducted among the 100 students. Students willing to participate in the study were included i...
ROLE OF STRAIN ELASTOGRAPHY IN OBSTETRICS AND GYNECOLOGY: PICTORIAL ESSAY OF OUR INITIAL EXPERIENCE
Ultrasonic elastography (real-time elastography, sonoelastography) is a new improvement of ultrasound technique and one of the various imaging modalities in the last few years which are being used for characterizing soft...
A COMPARATIVE CLINICAL STUDY OF KADALI KSHAR PRATISARAN AND INJ. SETROL IN THE MANAGEMENT OF ABHYANTAR ARSHA W.S.R. TO INTERNAL HAEMORRHOIDS.
There is a very peculiar role of “Kshar Karma” (an Anushastra), in the management of Arsha, as described by Sushrutacharya.Acharyas have mentioned Kadali as suitable for the Kshara formulation. Patients suffering from Ab...