Serum lactate as a predictor of outcome of sepsis – study
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Serum Lactate is known to be elevated in subjects with sepsis. Increased blood lactate levels are common in critically ill patients. Some studies revealed its association with prediction of morbidity and mortality. Hence this study was taken up to assess the levels of serum lactate in sepsis and its outcome. Materials and Method: This study comprised of age and sex matched groups consisting of 100 healthy individuals and 100 patients with septicemia who were admitted in MICU. Blood samples were collected and serum lactate levels were analyzed. Results: It was observed that serum lactate altered significantly (P< 0.0001) in subjects with sepsis when compared with healthy control group. The serum lactate levels were raised significantly high in cases with sepsis with outcome as death (P< 0.0001) in comparison to the subjects who had recovery. Conclusion: Hence serial lactate measurements would be useful as a very good predictor of morbidity and mortality during the course of sepsis in elderly individuals.
Authors and Affiliations
G. Lakshmi Chaitanya, D. Sridevi, Amrut A. Dambal, Sidrah . , Girija Menon
Dendritic cells and vitamin D in dry eye disease
To study the role of dendritic cells and vitamin D in troublesome evaporative dry eye diseasesMaterials and Methods This is a cross sectional study which includes 108 patients having evaporative dry eye disease and 86 no...
Association between Serum Uric Acid Levels and Hypertension: A Retrospective Study
Introduction: Elevated uric acid levels are frequently associated with lifestyle related diseases. Serum uric acid levels also have shown to play a very important role in the development of cardiovascular morbidity and r...
Fractional excretion of sodium (FENa): A paraphernalia in incipient nephropathy versus overt nephropathy in Type I Diabetes Mellitus
An estimated 40% of patients diagnosed with Type I diabetes and 5 - 15% of patients with Type II diabetes eventually develop ESRD and diabetes has become the leading cause (44%) of end-stage renal disease in India. There...
Association between type 2 diabetes mellitus and hypovitaminosis D
Introduction: Vitamin D is an important component in regulating the biological functions of the body in various ways. Many studies repeatedly explained the role of vitamin D in the pathogenesis and treatment of various d...
A correlation of plasma malondialdehyde, whole blood glutathione peroxidase and lipid profile in pulmonary tuberculosis
Background: Tuberculosis is one of the commonest chronic infectious diseases; highly endemic in India, kills five lakh patients every year. Oxidative Stress plays important role in inflammatory & degenerative diseases in...