Serum Level of Anti-CCP in Patients with Active Pulmonary Tuberculosis
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Background: Tuberculosis (TB) is a major public-health problem which principally affects the lungs, but may present a variety of rheumatic manifestations, simulating rheumatologic disorders such as rheumatoid arthritis. Methods: The main aim of this research was examined the anti- ccp level in 40 patient with active tuberculosis and 40 normal person’s serum by ELISA. Results: Mean levels of anti-CCP were significantly increased (p<0.01) in patients with TB compared with controls: 29.8 (17.7) vs. 10.8(7.9) U/ml, respectively. Conclusion: Finally, a high percent of patient with active TB show an increased level of anti–ccp that could make difficulties to detecting TB Arthritis.Tuberculosis (TB) is a major cause of human mortality and a worldwide public health problem .TB is a chronic, communicable disease caused by M. tuberculosis made distinctive by a destructive necrotizing granulomatous tissue response to the organisms. Mycobacterium tuberculosiscauses two million deaths every year and every year 8 million of new cases of TB are diagnosed worldwide [1,2]. Both pulmonary TB and also cases of extra pulmonary disease are increasing [3]. About 10% of extra pulmonary TB affects the bones and joints [4]. Tuberculosis of bones and joints often presents as graduallyworsening arthritis. Systemic and pulmonary symptoms are frequentlyabsent, and the differential diagnosis must include other possiblecauses of septic osteoarticular disease, inflammatory arthritis.
Authors and Affiliations
Sahar Emami
Keywords
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- EP ID EP569428
- DOI 10.26717/BJSTR.2017.01.000338
- Views 183
- Downloads 0
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