Serum Lipid Profile: A cellular signature in occurrence and progression of potentially malignant disorders and oral cancer
Journal Title: Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology - Year 2018, Vol 4, Issue 1
Abstract
Introduction and objectives Serum lipid profile is used to measure the systemic health status of an individual The objective of the study was to evaluate and correlate serum lipid profile in patients with potentially malignant disorders oral cancer and controlsMaterials and Methods This study was conducted on a sample of 150 subjects in which the subjects were divided into three groups with 50 subjects in each group The subjects in Group I were Controls CT Group II were Potentially Malignant Disorder PMD and Group III were Oral Cancer OC Out of 150 subjects 50 subjects were diagnosed as potentially malignant disorder and 50 were diagnosed as oral cancer based on histopathological diagnosisResults When results of group III were compared and correlated to subjects of group I a decrease in TC HDL LDL and VLDL was elicited When results of group II were compared and correlated to subjects of group I a decrease in TC HDL LDL and VLDL was elicited Triglycerides was not significantly altered in the studyInterpretation and Conclusion The results of our study showed an evidence of an inverse relationship between serum lipid profile and oral cancer and potentially malignant disorders The lower serum lipid status may be considered as an indicator to reflect the initial changes occurring in neoplastic cells thus substantiating their use as a diagnostic adjuvant in monitoring the oral cancer and potentially malignant disorderKeywords Blood serum Potentially Malignant Disorder Oral Cancer Serum Lipid Profile
Authors and Affiliations
Rashmi K, Vathsala Naik, Raghavendra Kini, Stuti Goyal
Keywords
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- EP ID EP479767
- DOI 10.18231/2395-6194.2018.0003
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