SERUM SODIUM CHANGES IN NEONATES RECEIVING PHOTOTHERAPY FOR NEONATAL HYPERBILIRUBINEMIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 27
Abstract
BACKGROUND: Neonates receiving phototherapy have side effects like hypocalcemia and electrolyte changes. Our study is hereby intended to study the serum sodium changes due to phototherapy. AIMS: To evaluate the serum sodium changes in neonates receiving phototherapy for neonatal hyperbilirubinemia. SETTINGS AND DESIGN: A prospective hospital based comparative study conducted on neonates admitted in the Neonatal Intensive Care Unit receiving phototherapy. METHODS AND MATERIAL: A predesigned proforma has aided the enrollment of 252 newborns into the study. Serum bilirubin and serum sodium were determined before and after termination of phototherapy. The first samples were considered as controls. A comparative study was made between before and after phototherapy groups to determine the incidence of serum sodium imbalances. STATISTICAL ANALYSIS USED: Proportions will be compared using chi-square test. All data of various groups will be tabulated and statistically analyzed using suitable statistical tests (Student's t test). RESULTS: Male to Female ratio was 1.45:1. Incidence of low birth weight babies was 23% and preterm was 20.2%. Mean birth weight and gestational age was 2.84±0.51 kg and 38.44±1.98 wks respectively. Mean duration of phototherapy was 37.65±11.06 hrs. The incidence of hyponatremia post phototherapy found to be 6% which was more in low birth weight (LBW) babies (17.2%, p<0.001) and preterm neonates (17.6%, p<0.001) than in normal weight babies (2.6%) and term neonates (3.1%) and in 17.4% babies when duration of phototherapy was >48 hrs (p<0.001). Even the decline in mean serum sodium values after phototherapy found to be statistically significant. CONCLUSION: Our study shows that neonates under phototherapy are at higher risk of hyponatremia. This risk is greater in premature and LBW babies and hence this group of babies should be closely monitored for changes in serum sodium and should be managed accordingly.
Authors and Affiliations
Sunil Kumar P, Uday Shankar S
Keywords
Related Articles
- EP ID EP230986
- DOI 10.18410/jebmh/2015/566
- Views 99
- Downloads 0
THE EFFECTIVENESS AND SAFETY OF FOLEY’S CATHETER WITH EXTRAAMNIOTIC SALINE INFUSION (EASI) ON CERVICAL RIPENING AND INDUCTION OF LABOUR
BACKGROUND The favourability of cervix is of fundamental importance for successful induction of labour. Unfavourable cervix should be ripened before induction is started. The various methods available for cervical ripeni...
PROGNOSTIC UTILITY OF GLASGOW ALCOHOLIC HEPATITIS SCORE (GAHS) IN ALCOHOLIC HEPATITIS
BACKGROUND Severe alcoholic hepatitis is associated with high mortality, 40-50% mortality at one month has been reported. Many scoring systems have been applied to predict survival in alcoholic hepatitis. Patients with h...
RENAL REPLACEMENT LIPOMATOSIS- A CASE REPORT
PRESENTATION OF CASE A non-obese 45 yrs. female patient presented with complaints of right loin swelling and pain on & off for 5 yrs. Physical examination revealed tenderness in right lumbar region and no palpable mass....
RELATIONSHIP OF GALL BLADDER PERFORATION AND BACTERIOBILIA WITH OCCURRENCE OF SURGICAL SITE INFECTION FOLLOWING LAPAROSCOPIC CHOLECYSTECTOMY
BACKGROUND Surgical site infection (SSI), a significant postoperative complication, can lead to considerable patient morbidity and mortality1 . Preventing postoperative infection is an essential factor in improving the r...
CLINICAL PROFILE OF HYPONATRAEMIA IN A TERTIARY CARE HOSPITAL
BACKGROUND Hyponatraemia is the most common electrolyte disorder among hospitalised patients occurring in upto 22% of hospitalised patients.1 David B Mount defined hyponatraemia as a serum sodium concentration (Na+) less...