SERUM SODIUM CHANGES IN NEONATES RECEIVING PHOTOTHERAPY FOR NEONATAL HYPERBILIRUBINEMIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 27
Abstract
BACKGROUND: Neonates receiving phototherapy have side effects like hypocalcemia and electrolyte changes. Our study is hereby intended to study the serum sodium changes due to phototherapy. AIMS: To evaluate the serum sodium changes in neonates receiving phototherapy for neonatal hyperbilirubinemia. SETTINGS AND DESIGN: A prospective hospital based comparative study conducted on neonates admitted in the Neonatal Intensive Care Unit receiving phototherapy. METHODS AND MATERIAL: A predesigned proforma has aided the enrollment of 252 newborns into the study. Serum bilirubin and serum sodium were determined before and after termination of phototherapy. The first samples were considered as controls. A comparative study was made between before and after phototherapy groups to determine the incidence of serum sodium imbalances. STATISTICAL ANALYSIS USED: Proportions will be compared using chi-square test. All data of various groups will be tabulated and statistically analyzed using suitable statistical tests (Student's t test). RESULTS: Male to Female ratio was 1.45:1. Incidence of low birth weight babies was 23% and preterm was 20.2%. Mean birth weight and gestational age was 2.84±0.51 kg and 38.44±1.98 wks respectively. Mean duration of phototherapy was 37.65±11.06 hrs. The incidence of hyponatremia post phototherapy found to be 6% which was more in low birth weight (LBW) babies (17.2%, p<0.001) and preterm neonates (17.6%, p<0.001) than in normal weight babies (2.6%) and term neonates (3.1%) and in 17.4% babies when duration of phototherapy was >48 hrs (p<0.001). Even the decline in mean serum sodium values after phototherapy found to be statistically significant. CONCLUSION: Our study shows that neonates under phototherapy are at higher risk of hyponatremia. This risk is greater in premature and LBW babies and hence this group of babies should be closely monitored for changes in serum sodium and should be managed accordingly.
Authors and Affiliations
Sunil Kumar P, Uday Shankar S
Keywords
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- EP ID EP230986
- DOI 10.18410/jebmh/2015/566
- Views 108
- Downloads 0
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