Abstract

Background: Cardiovascular disease (CVD) has become a major health issue in India&is probably one of the most preventable disease. Studies have quoted serum uric acid (SUA)&killip class as bad prognostic indicator in patients of myocardial infarction (MI). Objective: This study aims to find the role of SUA&killip classification as prognostic marker in patients of MI. Material & methods: Fifty patients of acute MI fulfilling the inclusion and exclusion criteria were compared with 50 age and sex matched healthy controls. A detailed history and physical examination with special reference to Killip class was carried out. Patients were followed up till hospital stay&then in OPD. SUA was measured on day 0, 3, 7 and also on day 30 of MI. SUA levels&Killip class was compared with coefficient of correlation. Results: There was a statistically significant higher level of SUA in patients of acute MI on day of admission as compared to controls (p < 0.05). At the time of admission, patients in killip class III&IV had higher SUA levels than those in class I&II. Four patients who died during follow up were in class IV. SUA levels are positively correlated to killip class i.e higher the SUA levels higher is Killip class. Conclusion: Higher SUA&higher killip class can be considered as indicator of bad prognosis in patients of MI.

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