Serum Uric Acid Level as a Prognostic Factor in Benign Essential Tremor
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 7, Issue 7
Abstract
Objective: Decreased serum uric acid has been associated with neurodegenerative diseases such as Parkinson’s disease (PD) in the elderly. Several studies suggest that there may be a link between PD and Essential tremor (ET) which is thought to be a neurodegenerative disease. Serum uric acid level (UA) and its relationship with prognosis in ET patients have not been addressed. Study Population: The current study was conducted in the outpatient neurology unit of Istanbul Medeniyet University Medical Faculty Göztepe Teaching Hospital between May 2011 and Sep 2013. Methods: Subjects with ET were evaluated. We collected serum samples to determine biochemical indicators including UA, glucose, blood lipids, liver function, and renal function. All the patients with vascular risk factors, dementia, depression or other neurodegenerative disorders were excluded, as were the subjects on uric acid-lowering therapy or with serious illnesses such as severe anemia, chronic renal failure, hepatic disease or active or ongoing cardiovascular or cerebral vascular disease. One hundred and sixteen subjects (52 isolated ET patients and 64 healthy controls well matched in comparison of age and sex) were enrolled. Results: UA level was similar between the groups. Follow-up UA levels of the patients were similar to controls, too. UA level correlated to age, ET starting age, cholesterol level and creatinine level (p<0.05). Conclusion: There were reasonable epidemiological evidences to support a link between ET and UA level, but we did not find any difference between serum UA levels of ET patients and controls in follow-up. Age was one of the factors contributing to the increased content of UA in the blood serum of especially the man with ET. These findings also supported the knowledge about isolated form of ET which was stable and benign.
Authors and Affiliations
Koçer Abdulkadir, Okay Münevver, Hasirci Buse, Ağırcan Dilek, Varoğlu Asuman
Keywords
Related Articles
- EP ID EP347853
- DOI 10.9734/BJMMR/2015/15960
- Views 61
- Downloads 0
The Effects of Supervised Exercise Program on Health-Related Physical Fitness in Kuwait
Aims: Physical activity improves health in terms of cardiovascular fitness, musculo-skeletal fitness, body composition, and metabolism. The study aims to examine the effects of supervised exercise training on metabolic p...
Oral Health Advices and Illustrations Card for Use in Mother-and-Child Health Clinics: Face and Content Validity
Background: The prevalence of Early Childhood Caries (ECC) in Peruvian children is very high especially in sub-urban areas. The dental profession is unable to solve this problem alone. Nurses have close contact with moth...
Metastatic Epithelioid Sarcoma ES with Pneumothorax, Hemoptysis and Thoracic Radiographic Bilateral Cavity Lesions in Young Male Patient – Case Report
Epithelioid sarcoma is a rare soft tissue sarcoma in young adults (20-39 year olds) involving the upper extremities 60% of the time. The incidence of upper extremity epithelioid sarcoma was 0.1 cases per million per year...
Use of Cranial Computed Tomography (CT) in Elderly Patients Presenting After a Fall: Can We Predict Those Having Abnormal Head CT Scans
Aims: Identify factors predictive of increased risk of intracranial injury and assess the ability of the non-age related components of the New Orleans head CT criteria (NOC) to guide decision-making. Study Design: Retros...
Endovascular Reduction of Splenic Blood Flow in the Treatment of Patients with Liver Cirrhosis
Purpose: Defining the effectiveness of the embolization of the splenic artery (ESA) in the treatment of patients with liver cirrhosis. Materials and Methods: We have analyzed the results of treatment 318 patients with ci...