Serum Vitamin D Status in Women with Preeclampsia in Ibadan, Nigeria - A Case-Control Study
Journal Title: Journal of Applied Life Sciences International - Year 2017, Vol 14, Issue 4
Abstract
Aims: Preeclampsia is one of the most common complications of pregnancy characterized by high blood pressure, proteinuria and edema. Recent studies suggest that there is a possible link between Vitamin D status and preeclampsia. There is little knowledge on vitamin D status of pregnant and preeclamptic women in this region. This study was carried out to assess serum levels of 25-hydroxy Vitamin D (25(OH)D3) in normotensive pregnant women and preeclamptic women in Ibadan, Nigeria. Study Design: Case-Control Study. Place and Duration of Study: One hundred and twenty women were recruited from Antenatal Clinic of University College Hospital (UCH), Ibadan and Adeoyo Maternity Clinic, Ibadan between January 2016 to August 2017. Sixty normotensive pregnant women (mean age 32.1± 4.8) as control and sixty preeclamptic women (mean age 33.4± 3.2) as case group. Blood samples were collected at 2nd, 3rd trimester and postpartum. Methodology: Serum 25-hydroxyvitamin D level was quantified by Enzyme Linked immunosorbent assay (ELISA), and data obtained were analyzed with Student t-test and One way analysis of Variance (ANOVA). Results: Results showed that preclamptic women had significantly lower levels (P<.05) of Vitamin D at 20 weeks (24.5±4.6 vs 36.59±5.1), 30 weeks (23.8±3.9 vs 34.14±3.7), and postpartum (21.7±5.5 vs 32.62±3.2) when compared to control group. The results of this study show that there is Vitamin D insufficiency in preeclamptic women in the study environment. Conclusion: Vitamin D insufficiency might be associated with preeclampsia. Vitamin D supplementation and diets rich in Vitamin D, can help to reduce the risk of preeclampsia and also be a possible target for improved pregnancy outcomes in preeclampsia.
Authors and Affiliations
Ayobola Abimbola Sonuga, Modupe Fisayo Asaolu, Oyebola Oluwagbemiga Sonuga
Keywords
Related Articles
- EP ID EP318067
- DOI 10.9734/JALSI/2017/37632
- Views 73
- Downloads 0
Comparative Study on Antibacterial and Selected Antioxidant Activities of Different Eryngium foetidum Extracts
Eryngium foetidum is an herb which is used as a medicinal and a spice plant in tropical regions. This plant is used in traditional medicine in treating conditions such as fever, chills, vomiting diarrhea, stomach aches,...
Maximizing Maize (Zea mays L.) Crop Yield via Matching the Appropriate Genotype with the Optimum Plant Density
Aim: The objective of this investigation was to match the functions of optimum plant density to produce the highest possible grain yield per unit area with the greatest maize genotype efficiency. Study Design: A split pl...
The Effects of Boric Acid on Fiberboard Properties Made from Wood/Secondary Fiber Mixtures: Part 4. Insulation Properties of Boards
The boards made from wood and secondary fibers appear to be well correlated secondary fiber/wood fiber proportions in terms of the behavior of the sound acoustic properties. However, boards were generally shown better ac...
Physiological and Agronomic Performance of Domesticated and Wild Cotton Germplasm from Selected Regions of Kenya
Aims: Cotton (Gossypium species) occupies a prime position as a fibre crop of the world used for making cooking oil, soup and seed cake for animal feed industry among other uses. Performance of wild cotton germplasm in K...
Biomass Saccharification and Screening for Production of Pectinase from Physocladia obscura JEL 513
Aim: This study documents for the first time the production of pectinase by Physocladia obscura JEL 513 and the optimization of its production in solid-state fermentation. Study Design: OFAT (One Factor At a Time). Plac...