Several issues in the surgical treatment of intrahepatic cholangiocarcinoma
Journal Title: Journal of Clinical Hepatology - Year 2024, Vol 40, Issue 12
Abstract
Intrahepatic cholangiocarcinoma (ICC) ranks second among malignant liver tumors and has high malignancy and poor prognosis. Currently, surgical treatment remains the only potentially curative therapy for ICC, but with a relatively low R0 resection rate and a short recurrence-free survival time after surgery. There are still several issues that need to be clarified, such as reasonable margin width, the value of anatomical hepatectomy, the role of lymph node dissection, and the oncological efficacy of laparoscopic liver resection and liver transplantation. This article reviews the research advances in surgical treatment strategies for ICC and related controversies, in order to provide a reference for clinical decision-making.
Authors and Affiliations
Anfeng SI, Zhengqing LEI, Zhangjun CHENG
Guideline for diagnosis and treatment of liver failure (2024 version)
Liver failure is a severe clinical syndrome of liver disease with an extremely high mortality rate. Over the years, scholars worldwide have continuously investigated various aspects of liver failure, including its defi...
Causal association of liver function and lipid metabolism levels with sleep disorders based on Mendelian randomization
[Objective] To investigate the causal association of liver function and lipid metabolism levels with sleep disorders based on the Mendelian randomization analysis. [Methods] The analysis was conducted using the data from...
High-risk factors for early postoperative recurrence of hepatocellular carcinoma and related prediction methods
Hepatocellular carcinoma (HCC) is a malignant tumor with high incidence and mortality rates, and although surgical resection is a possible method for cure, the prognosis of HCC is still affected by its high recurrenc...
Research advances in the mechanism of action of nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome in autoimmune hepatitis
Autoimmune hepatitis (AIH) is chronic hepatitis caused by the attack of live cells by the immune system, and at present, the pathogenesis of AIH remains unclear. Inflammasomes are important components of innate immun...
Interpretation of REDISCOVER international guidelines on the perioperative care of surgical patients with borderline-resectable and locally advanced pancreatic cancer (2024)
The REDISCOVER international guidelines on the perioperative care of surgical patients with borderline-resectable and locally advanced pancreatic cancer were released in July 2024, and based on the existing clinical cha...