Severe Alopecia Complicating Systemic Sclerosis
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 2
Abstract
Aims: To describe a case of systemic sclerosis (SSc) associated with severe alopecia areata (AA) responsive to topical and systemic treatments, including vasoactive and immunosuppressive drugs (mycophenolate mofetil). Presentation of the Case: A 56 year old woman, affected by SSc as from 5 years back, developed a rapid hair loss that progressively involved a large area of the scalp. AA was diagnosed, after the exclusion of an overlapping systemic lupus erythematosus or fungal infection. Treatment with topical steroids and minoxidil, plus mycophenolate mofetil that was introduced for interstitial lung disease, led to progressive improvement of alopecia up to a complete resolution within 4 months. Discussion: This is an interesting observation of SSc complicated by severe AA, which is often observed in patients affected by various autoimmune disorders. A possible common pathogenesis of AA and SSc is also discussed.
Authors and Affiliations
Dilia Giuggioli, Michele Colaci, Giulia Cassone, Clodoveo Ferri
Keywords
Related Articles
- EP ID EP348445
- DOI 10.9734/BJMMR/2015/19589
- Views 48
- Downloads 0
Falls in Elderly with Plantar Changes
Aims: The purpose of this study was to evaluate the prevalence of falls among older people with plantar changes in order to preserve their autonomy and independence. Study Design: A cross-sectional, descriptive, analytic...
Pseudo-hypoparathyroidism Coexistent with Systemic Sclerosis: A Rare Case Report
Background: Systemic sclerosis is a chronic autoimmune inflammatory disease with wide-spread fibrosis of the skin and internal organs. The hypoparathyroidism associated with systemic sclerosis is infrequent and rarely re...
Obesity Effects on Bone Femur Tissue of Animals Subjected to Obesity through High-fat Diet
Introduction: Adipose corporal tissue accumulation may cause alterations in the bone metabolism and might influence its properties. However, there are still many controversies, in addition to how the adipose tissue can c...
Thromboprophylaxis for Intensive Care Patients
The advent of low-molecular-weight heparin (LMWH) marked a new chapter in the prevention of venous thromboembolism. The enviable pharmacokinetic properties associated with this class of medication, ensured the place of L...
The Relationship between Gestational Diabetes, Enamel Hypoplasia and DMFT in Children: A Clinical Study in Southern Iran
Background: Odontogenesis begins from the sixth week of fetal life; meanwhile, the subsequent evolution is very complex and takes a long time. As a part of odontogenesis, amelogenesis can be altered by local and systemic...