Severe Hyperparathyroidism Versus Parathyroid Carcinoma A clinical dilemma
Journal Title: Sultan Qaboos University Medical Journal - Year 2010, Vol 10, Issue 1
Abstract
No clinical or laboratory data allow a preoperative diagnosis of parathyroid carcinoma and only occasionally does a defnitive fnding differentiate an adenoma from a carcinoma. We present a case of primary hyperparathyroidism presenting with severe elevation of parathyroid hormone and serum calcium as well as complications. We go on to discuss the case in the light of a literature review. Te severity of the elevation of the parathyroid hormone, other biochemical alterations, the presence of skeletal and renal complications and of a neck mass should alert the clinician to a possible parathyroid carcinoma. Radical surgery is the only effective therapy for parathyroid carcinoma, and should always be performed if a preoperative suspicion is entertained.
Authors and Affiliations
Mariam Al-Fadhli| Departments of Medicine, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait, Suhail A R Doi| Departments of Medicine, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait and School of Population Health, University of Queensland, Brisbane, Australia, Tomas Muttikkal| Departments of Radiology, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait, Basel Al-Sumait| Departments of Surgery, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait
Keywords
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