Severe Obtructive Sleep Apnea Syndrome – Juvenile Myastenia Gravis Case Requiring Non-invasive Mechanical Ventilation Treatment
Journal Title: Kocaeli Tıp Dergisi - Year 2017, Vol 6, Issue 3
Abstract
Obstructive Sleep Apnea Syndrome (OSAS) which is often diagnosed lately is an emergency. We present a 15 years old girl who is diagnosed as OSAS and juvenile Myasthenia Gravis (MG) with clinical and laboratuary findings to attract attention to the subject. Her polysomnography (PSG) result was consistent with severe OSAS (Apnea index 96.7/hour, apnea-hypopnea index 148/hour). MG was thought due to diurnal variation of muscle strength and increase of muscle weakness after exercise. Significant clinical response to pridostigmine supported diagnosis. After initiation BIPAP with mask during sleep, carbondioxide retantion decreased (pCO2: 46mmHg)
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