Sex-determining region y (SRY)-Box2 (SOX2) & L1-cell adhesion molecule (L1CAM) expressions in endometrioid carcinoma of the uterus; An Immunohistochemical Study
Journal Title: Annals of Cytology and Pathology - Year 2018, Vol 3, Issue 1
Abstract
Background: activation of cancer stem cells and disturbances in cell adhesion pathways are recently incriminated in endometrioid carcinoma progression, invasion and metastases which consequently leads to dismal patients outcome. Sex-determining region y (SRY)-Box2 (SOX2) is a member of SOX family and it has many roles in malignant stem cells control. L1-cell adhesion molecule (L1CAM) is a membrane glycoprotein which is a member of immunoglobulin family. The aim of the work: is to evaluate prognostic, clinical and pathological values of Sox2& L1CAM expression in tissues of endometrioid carcinoma of the uterus.
Authors and Affiliations
Salem Amir M, Mahdy Entsar R
Keywords
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- EP ID EP555736
- DOI 10.17352/acp.000010
- Views 47
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