Short term memory, physical fitness, and serum brain-derived neurotrophic factor in obese adolescents
Journal Title: Paediatrica Indonesiana - Year 2015, Vol 55, Issue 5
Abstract
Background Obesity in adolescents is a major health problem and has been associated with low academic achievement. Brainderived neurotrophic factor (BDNF), a neurotrophin, plays a role in appetite suppression and memory, and its secretion is enhanced by physical activity. This neurotrophin may be associated with academic achievement in obese. Objective To compare physical fitness and serum BDNF levels to short term memory levels in obese adolescents aged 10–14 years. Methods This comparative, cross-sectional, analytic study was carried out on 40 elementary and high school students in Bandung, West Java, who were recruited by stratified random sampling. Short term memory was assessed by a psychologist using the Wechsler Intelligence Scale for Children-III Digit Span test (WISC-III Digit Span). Physical fitness was assessed by a clinical exercise physiologist using the Asian Committee on the Standardization of Physical Fitness Test (ACSPFT). Serum BDNF levels were measured by ELISA test in a certified laboratory. ANOVA test was used to assess for a correlation between serum BDNF concentration and short term memory, as well as between physical fitness level and short term memory. Pearson’s correlation test was used to analyze for a correlation between serum BDNF and physical fitness levels. Results The majority of subjects were in the physical fitness categories of moderate or poor. Subjects had a mean BDNF level of 44,227.8 (SD 10,359) pg/mL. There was no statistically significant difference in physical fitness with either serum BDNF or with short term memory levels (P=0.139 and P=0.383, respectively). Also, no correlation was determined between serum BDNF and physical fitness levels (r=0.222; P=0.169). Conclusion In obese adolescents, short term memory levels are not significantly different between physical fitness levels nor between serum BDNF levels.
Authors and Affiliations
Rini Rossanti, Dida Gurnida, Eddy Fadlyana
Keywords
Related Articles
- EP ID EP448567
- DOI 10.14238/pi55.5.2015.277-81
- Views 78
- Downloads 0
Upper arm fat and muscle in stunted and non-stunted children aged 0-24 months
Background The prevalence of stunting in Indonesia is high, with particularly negative impacts on health during childhood as well as adolescence. Stunting impacts the health of children as well as adults, especially with...
The effect of regular aerobic exercise on urinary brain-derived neurotrophic factor in children
Background Nervous system development in early lifeinfluences the quality of cognitive ability during adulthood.Neuronal development and neurogenesis are highly influencedby neurotrophins. The most active neurotrophin is...
Blood pH and urinary uric acid-creatinine ratio in newborns with asphyxia
Background Asphyxia is one of the leading causes of death in the world. Prematurity (28%), sepsis (26%), and asphyxia (23%) are the most common causes of death in newborns. In Indonesia, the newborn mortality incidence i...
The role of genetic variation in TCF7L2 and KCNJ11, dietary intake, and physical activity on fasting plasma glucagon-like peptide-1 in male adolescents
Background Transcription factor 7-like 2 (TCF7L2) and potassium voltage-gated channel subfamily j member 11 (KCNJ11) gene polymorphisms have been associated with type 2 diabetes mellitus (T2DM) via regulation of insulin...
Clinical and molecular analysis of Noonan syndrome in Indonesia: a case report
Noonan syndrome (NS; OMIM#163950) is a relatively common autosomal dominant disorder with a worldwide prevalence of approximately 1:1,000 to 1:2,500. The syndrome is characterized by distinctive facial features, congenit...