Significance of Alanine Amino Transferase [ALT] in Diabetic Patients with Hearing Impairment
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 12
Abstract
Abstract: In diabetes mellitus, hearing impairment1 is a common complication. It occurs due to microangiopathy affecting cochlear blood vessels and neuropathy affecting cochlear nerve. This study is to find the significance between alanine amino transferase level and hearing loss in diabetic patients2. This cross sectional study includeshundred diabetic patients attending tertiary health care centre. Serum alanine amino transferase levels were assayed by enzymatic method, blood glucose by glucose oxidase-peroxidase method3, HbA1c by Immuno turbidometry method& hearing by Pure-tone audiometry. Out of 100 diabetic patients, 68 hadalanine amino transferase level> 45 IU/L, & out of 68 diabetic patients withalanine amino transferase levels >45 IU/L, 53had hearing loss which is significant. From the results obtained, we find that the hearing impairment in diabetic patients is associated with elevated alanine amino transferase. Hence in the screening of diabetic patients, ALT level should also be included.
Authors and Affiliations
Vidhyalogini T, Sumathi K
Keywords
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