SIGNIFICANCE OF LACTATE DEHYDROGENASE AND ASPARTATE TRANSAMINASE AS BIOCHEMICAL MARKERS AND AS PREDICTORS OF SEVERITY OF PREGNANCY-INDUCED HYPERTENSION AND ITS COMPLICATIONS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 20
Abstract
BACKGROUND To compare serum Lactate Dehydrogenase (LDH) and serum Aspartate Transaminase (AST) of normotensive pregnant women with those of preeclamptic and eclamptic women. To determine the relationship of levels of serum lactate dehydrogenase and serum aspartate transaminase with severity of pregnancy-induced hypertension and its complications. MATERIALSAND METHODS The study was carried out on pregnant hypertensive patients attending outpatient department of Obstetrics and Gynaecology department, AMCH, Dibrugarh, Assam from 1st July 2013 to 30th June 2014. Normotensive pregnant women were taken as controls. Each serum sample from both the control group as well as study group was estimated for lactate dehydrogenase and aspartate transaminase using standard methods and a comparison is drawn and analysed using t-test and Chi-square test. RESULTS Serum lactate dehydrogenase and serum aspartate transaminase levels were higher in the study group in comparison to the study groups. The mean serum LDH was 198±30.03U/L in control group, whereas in preeclampsia and eclampsia, mean serum levels of LDH were 817±114U/L and 927±108U/L, respectively. The levels of the serum AST were found to be less than 600U/L in normotensive and preeclampsia patients and more than 600 U/L in eclampsia and other complications of PIH. CONCLUSION Serum lactate dehydrogenase and serum aspartate transaminase levels in patients suffering from preeclampsia and its complications are consistently higher compared to the normotensive pregnant patients. To determine the usefulness of inclusion of these enzymes along with other cardiac enzymes in the panel of investigations of pregnant women universally needs further large scale comparative studies.
Authors and Affiliations
Ramesh Sonowal, Rupinder Kaur
Keywords
Related Articles
- EP ID EP215193
- DOI 10.18410/jebmh/2017/221
- Views 78
- Downloads 0
RETINOPATHY OF PREMATURITY- A CLINICAL STUDY
BACKGROUND The aim of the study is to detect the incidence of retinopathy of prematurity among low birth weight and preterm infants and identification of potential risk factors for retinopathy of prematurity. MATERIALS A...
FOETAL-VITELLINE DUCT CYST WITH HINDGUT AGENESIS- A RARE CASE REPORT
BACKGROUND This is a case of 22-year-old female patient with 14 weeks live foetus, underwent routine ultrasound scan where a large intraabdominal cyst was found. Foetus has been aborted and later subjected to autopsy whe...
CAPILLARY HEMANGIOMA OF THE PARANASAL SINUSES
OBJECTIVE: To report a case of ethmoid sinus capillary hemangioma and to discuss its management and treatment options with special mention on the clinical presentation, radiographic features and surgical options. METHOD:...
STUDY ON THE EFFECTIVENESS OF DRUGS USED FOR CERVICAL DILATATION TO REDUCE DURATION OF LABOUR AND FOETAL OUTCOME
BACKGROUND Normal labour is a difficult processes characterised by uterine action leading to cervical dilation and effacement followed by delivery of the foetus. Any procedure or drug, which decreases the duration of lab...
CASE REPORT- MANAGEMENT OF UNILATERAL CLCP PATIENT BY NASOALVEOLAR MOLDING
Clefts of the lip and palate unfortunately are by far the most common major facial malformations in mankind. Fortunately, as a result of technical advancements in the fields of medicine and their families for treatment,...