Significance of Masood’s Scoring Index in Cytological Diagnosis of Palpable Breast Lumps: A 3 Years Restrospective Studies
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 10
Abstract
Introduction: Breast lump is the commonest presentation of breast diseases. Diagnosis of breast diseases can be made out based on history, physical examination and investigations, like cytology, histology and radiology. Several studies have shown that triple tests consisting of clinical, cytopathological and radiological examinations are more accurate, when all the three are positive; the accuracy approaches almost 100% for malignancy. Materials and methods: A 3 years retrospective study was performed in the Department of Pathology in a tertiary care centre. The cytological slides and corresponding histological slides were retrieved from the archives, and the cytological smears of palpable breasts were assessed. Statistical analysis: concordance study between conventional, MMSI and comparison with Histopathology. Results: A total 226 patients with palpable breast lump were included in the study. A total of 18 cases were diagnosed by histopathology and there was 100% correlation between conventional and post MMSI diagnosis. A total of 144 cases were diagnosed in this category by histopathology 134 (94.4%), cases showed correlation, whereas 2 (1.4%) were under diagnosed as non proliferative breast diseases and 6 (4.2%) were over diagnosed as carcinoma by conventional cytology. Proliferative breast diseases with atypia. Out of 6 cases diagnosed on histopathology, MMSI showed 100% correlation, whereas conventional cytology 2 cases were under diagnosed as category 2 and 2 cases were correctly categorized as category 3, and 2 cases were over diagnosed as category 4. Carcinoma in situ/ Carcinoma. Out of 58 cases diagnosed by histopathology, 52 (89.7%) showed correlation with MMSI and conventional smears. 6 (10.3%)cases were under diagnosed and categorized as category 3 by MMSI. 4 cases (6.9%) were under diagnosed and categorized as category 2 and 2 cases (3.4%) were under diagnosed and categorized to category 1 by conventional cytology. Conclusion: The present study concludes that Masood’s modified scoring index has better diagnostic accuracy than conventional cytology method in diagnosing proliferative breast diseases without atypia and proliferative breast diseases with atypia, which is very useful in management of patents.
Authors and Affiliations
Jignasha M. Patel
Keywords
Related Articles
- EP ID EP529623
- DOI 10.21088/ijprp.2278.148X.71018.4
- Views 48
- Downloads 0
Prevalence of Thyroid Lesions in a Rural Setting: A Cytological Study from a Tertiary Care Teaching Hospital
Background: The past few years have witnessed a global increase in the prevalence of thyroid cancer, and it is the fifth most common cancer in women. The study intends to estimate the prevalence of thyroid malignancies,...
Retrospective Analysis of Coagulation Profile in Pregnancy Induced Hypertension Cases in a Tertiary Care Hospital
Background: It is a physiological process in women and is associated with risk to health of both mother and child. To prevent maternal and fetal morbidity and mortality by early assessment of severity of pre eclampsia an...
Histomorphological Pattern of Testicular Lesions in Orchidectomy Specimens: A Retrospective Study
Background: Testis is affected by various non neoplastic and neoplastic lesions. Non neoplastic lesions include congenital anomalies, inflammatory, infective, vascular lesions, cysts, and atrophy. The incidence of testic...
Immunohistochemical Correlation with Morphological Evolution of Urinary Bladder Tumors
Context: Urinary bladder diagnosis can be challenging and conventional markers used were cytokeratins. The new additions are GATA 3, uroplakin and S100P. This study helps to analyze immunohistochemical expression of pane...
Significance of Nuclear Morphometry in Evaluation of Squamous Intraepithelial Lesions in Vaginal Cytology: A Case Series Study
Context: Cervical cancer is the second leading malignancy in the women occurring worldwide. Researches based on nuclear morphometry on cervicovaginal smears are very much sparse; hence we have taken up this study. Aims:...