SIGNIFICANCE OF PAP SMEAR IN DETECTING ABNORMALITIES OF CERVIX IN HIV-INFECTED WOMEN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 95
Abstract
BACKGROUND In India, around 22% of total reported AIDS cases and 30% of newer HIV infections are among women. Reproductive tract morbidities are common in HIV-infected women and they are 10 times more likely to have abnormal Pap smears than HIV-negative women. Unlike most other cancers, carcinoma cervix is highly preventable when precursor lesions are detected and treated before they develop into cancer. This study mainly highlights the importance of cervical cytology in HIV-infected women and to increase the awareness of the value of Pap smear as an integral part of preventive care for HIV-infected women. MATERIALS AND METHODS The present study was undertaken in a total of 100 HIV-positive women attending Coimbatore Medical College Hospital over the period of two years. Correlation and statistical data analysis of colposcopic findings, Pap smear findings and CD4 count were studied. RESULTS In the present study, 45% of women had abnormal Pap smear, which included inflammation 14%, reactive atypia 6%, various organisms 20%; and epithelial abnormalities 5% which included squamous intraepithelial lesions and squamous cell carcinoma. 70.6% of women with abnormal colposcopic findings had abnormal Pap smear and 18.4% women with normal cervix had abnormal Pap smear. Abnormal Pap smears were reported in 46.9% of women with CD4 count ≤200, in 48.9% of women with CD4 count between 201-500 and in 50% of women with CD4 count between 501-700. Incidence of abnormal Pap smears increased in HIVinfected women, irrespective of colposcopic findings and CD4 counts. CONCLUSION This study concluded that all HIV-positive women should be regularly screened with Pap smear to diagnose lower genital tract neoplasia at the earliest, regardless of age, colposcopic findings and CD4 counts, so that they can be promptly and effectively treated.
Authors and Affiliations
Kavitha M, Pavithra T, Lalitha C
Keywords
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- EP ID EP280670
- DOI 10.14260/jemds/2017/1526
- Views 81
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