Silver Stained Nucleolar Organising Region (AgNOR) Count and its Correlation with Colposcopy in Suspicious Cervical Pathology
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 8
Abstract
Introduction: Colposcopy is considered a sensitive tool for screening of cervical malignancy. Colposcopy directed biopsy helps in confirming diagnosis. Silver stained nucleolar organising region (AgNOR count) of dysplastic cells further enhances the diagnosis. Aim: To study the correlation of AgNOR count and colposcopy in suspicious cervical lesions. Materials and methods: 200 women of reproductive age group were screened for cervical cancer and colposcopy directed biopsy taken. AgNOR count studied and correlated with HPE and Modified Reid’scolposcopic index. Results: There was a good correlation between AgNOR count and the degree of dysplasia. Also there was a good correlation of AgNOR count and Modified Reid’scolposcopic index. Conclusions: AgNOR count is simple, effective method and it adds strength to histopathology and colposcopy and also assess different grades of cervical intraepithelial neoplasia.
Authors and Affiliations
A. R. Nasreen Fathima
Keywords
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