Balapiravir plus peginterferon alfa-2a (40KD)/ribavirin in a randomized trial of hepatitis C genotype 1 patients

Introduction. Balapiravir (R1626, RG1626) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). This phase 2, double-blind international trial eval...

Skin manifestations of liver diseases

Portal venous gas. Report of three cases

When portal venous gas (PVG) is found, it is usually considered an ominous sign. It is now more frequently found because of the improvement in imaging studies, mainly through computed tomography (CT). It was first relate...

Chilaiditi syndrome. An uncommon cause of crampy, upper abdominal pain

Detection of hepatitis B activity in HBeAg-negative carriers with normal aminotransferase levels in central Brazil

Background and rationale for the study. Hepatitis B virus (HBV) chronic infection may follow a benigncourse with low risk of cirrhosis or liver cancer. As differentiation of inactive status from HBeAg-negative chronic he...