SIMPLE, FAST AND RELIABLE REVERSED PHASE HPLC METHOD FOR LORNOXICAM ANALYSIS IN PHARMACEUTICAL FORMULATIONS
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 2
Abstract
Analysis of active ingredients is very important process during drug development and formulation. In this work a simple, fast, economic and reliable analysis method of lornoxicam was developed and validated regarding linearity, specificity, sensitivity, precision and accuracy. limit of detection and limit of quantification were found to be The method was proven to be 0.122 and 0.061 μg/ml. the method consumed very little amount of mobile phase (about 4 ml per each sample). Also the developed analytical method of LOR was very fast which was indicated by a very small retention time (about 3.6 minutes). The analytical method was tested for detection of lornoxicam in commercial Xefo® 8 mg tablets and it was proven to be very effective.
Authors and Affiliations
Dr. Gamal M. Mahrous
Keywords
Related Articles
- EP ID EP666947
- DOI -
- Views 113
- Downloads 0
BACTERIAL DISEASES: HUMANS VS MICROORGANISMS
Bacteria, one among the group of microorganisms like virus, protozoa and fungi, is universally present in nature. It is in air, water and soil, the basic elements of life closely associated with all living organisms. Pre...
ALOE VERA GEL REVERSES HAEMOSTATIC DERANGEMENT IN RATS FOLLOWING SALT LOADING.
This research investigated the effect of Aloe vera (gel) on haemostatic status of high salt loaded rats. Twenty wistar rats (200-250g) were randomly assigned into 4 groups (n=5) thus: control, Aloe (600mg/kg of Aloe vera...
THE PREVALENCE OF RISK FACTORS OF DIABETES MELLITUS AMONG NORMAL POPULATION IN AL MADINAH AL MONAWARRAH
Background: There is a spread in the number of prevalence of DM in Saudi Arabia. This was the main motivation to start working on a method to identify individuals who had high score in the risk factor assessment. Objecti...
ANTIOXIDANT CAPACITY AND DNA DAMAGE PROTECTIVE ACTIVITY OF THE ROOT EXTRACT OF NAUCLEA LATIFOLIA
Damage to the genome caused by free-radicals is fundamental to the genesis of genetic diseases. Plants are rich in phytochemicals including tannin, saponin, flavanoids, alkaloids and phenolics, with a variety of metaboli...
QUALITY VERIFICATION OF SIX MEDICINES IN WHOLES AND HALVES TABLETS, RE-PACKAGED IN INDIVIDUAL PLASTIC COMPARTMENTS DURING SIXTY DAYS
Plastic boxes with individual compartments are often used to improve medication compliance and only a few studies have been done on the stability of the tablet halves after placing them on these devices. In this investig...