Simultaneous Determination and Validation of Hydrochlorothiazide & Eprosartan in bulk drug and Marketed Formulation by Rp-Hplc
Journal Title: International Journal of Pharmaceutical & Biological Archive - Year 2017, Vol 8, Issue 1
Abstract
Validation of developed and RP HPLC analytical method according to ICH Guidelines. A review of literature reveals that no analytical methods are available for these drugs. There are no methods in the literature for the estimation of drugs in combined dosage forms. Analytical methods have been report for hydrochlorothiazide and eprosartan using RP-HPLC in pharmaceutical dosage form. The development of simple and precise reverse phase high performance liquid chromatography of hydrochlorothizide and eprosartan using single method in bulk in bulk drug and market formulation.
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