SIMULTANEOUS DETERMINATION OF CURCUMIN AND GEFITINIB IN PURE FORM BY USING UV SPECTROPHOTOMETRIC METHOD
Journal Title: Hygeia:journal for drugs and medicines - Year 2017, Vol 9, Issue 1
Abstract
Plan: Development and Validation of a method for the UV simultaneous determination of curcumin and Gefitinib. Preface: U.V Spectrophotometric method have been widely employed in determination of individual components in a mixture or fixed dose combination. For the ternary mixture containing Curcumin and Gefitinib, no spectrophotometric method for simultaneous evaluation has been reported so far. Thus our aim is to develop simultaneous equation method for estimation of the ternary mixture using U.V spectrophotometry. Methodology: The method was validated as per ICH guidelines. The recovery studies confirmed the accuracy and precision of the method. Outcome: It was successfully applied for the analysis of the drug in bulk and could be effectively used for the routine analysis.
Authors and Affiliations
SAGAR Savale
ROLE OF PROPOLIS IN AUGMENTING THE BUCCAL MUCOADHESION- AN EXPERIMENT BASED REPORT
Plan: The present research has been undertaken with the aim to develop an oral mucoadhessive gel for gingivitis and periodontitis, evaluation of its physicochemical characteristics. Preface: Gingivitis and periodontitis...
Syntheses, Characterization and Antimicrobial screening of some Novel Benzimidazoles
Plan: Present work aims to synthesize a series of new benimidazoles (SBS-a-m) with various substitutions at 2-o-amino phenyl position and to evaluate their in-vitro antibacterial and anti-fungal activity. Prologue: Benzi...
PHYTOCHEMICAL STUDIES OF BIOACTIVE COMPOUNDS FROM Cucumis melo LINN.
Objective: The present study deals with the qualitative identification of phytochemical constituents from Cucumismelo Linn fruits and seeds Method: The methanolic extract of both fruit and seed was subjected to phytoch...
Studies on the antioxidant activity of Costus igneus leaf extract
Plan: The antioxidant activity studies of the extract of Costus igneus leaves Preface: Costus igneus commonly known as fiery costus or Spiral flag is a species of herbaceous plant. It is claimed to help build up insulin...
UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION FOR QUANTITATIVE ESTIMATION OF RUTIN
Plan: we have developed new a method for quantitative estimation of Rutin hence no UV spectroscopic method is available for the quantitative analysis of rutin for bulk analysis. Preface: U.V Spectrophotometric method ha...