SIMULTANEOUS ESTIMATION OF LOSARTAN POTASSIUM AND AMLODIPINE BESYLATE IN TABLET DOSAGE FORM BY UV SPECTROPHOTOMETER
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 4
Abstract
New UV spectrophotometric (UV method) for the quantitative estimation of Losartan potassium and Amlodipine, a potent anti-hypertensive agents in pure form and in solid dosage forms was developed in the present study. The linear regression equations for Losartan potassium was Abs=0.09xConc. (in μg/mL) and Amlodipine was Abs=0.015xConc. (in μg/mL) measured at 206 nm and 360 nm respectively. The results of analysis were treated statistically, as per ICH guidelines for validation of analytical procedures, and by recovery studies.
Authors and Affiliations
K. Kaveri , C. Saravanan , Tamizh Mozhi
Keywords
Related Articles
- EP ID EP124729
- DOI -
- Views 86
- Downloads 0
A NOVEL VALIDATED RP-HPLC METHOD FOR THE DETERMINATION OF ITOPRIDE HYDROCHLORIDE IN BULK AND PHARMACEUTICAL TABLET DOSAGE FORMS
A simple, specific, accurate, rapid, inexpensive isocratic Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) method was developed and validated for the quantitative determination of Itopride HCl in pharmace...
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF ATENOLOL AND CHLORTHALIDONE FROM PHARMACEUTICAL FORMULATION
A reverse phase high performance liquid chromatography (RP HPLC) method was developed and validated for the simultaneous estimation of atenolol and chlorthalidone in marketed formulation. The determination was carried ou...
SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW
Oral route still remains the favorite route of drug administration in many diseases and till today it is the first wayinvestigated in the development of new dosage forms. Approximately 40 per cent of new drug candidates...
PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION OF CELOSIA ARGENTEA LINN.
Celosia argentea Linn belongs to family Amaranthaceae and is being used in the indigenous systems of medicine as a wound healing and immune stimulating agent for curing kidney stone. The drug part is usually used as the...
A PHARMACEUTICAL APPROACH OF PEARL AS A BIOSAFE NANOMEDICINE
Mukta or Pearl, a valuable gem is included in Ratna varga in most of the Ayurvedic texts. As far as the Ayurvedic Pharmaceutical Science is concerned, selection of raw material is the nucleus of the present study which i...