SIMULTANEOUS ESTIMATION OF LOSARTAN POTASSIUM AND AMLODIPINE BESYLATE IN TABLET DOSAGE FORM BY UV SPECTROPHOTOMETER
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 4
Abstract
New UV spectrophotometric (UV method) for the quantitative estimation of Losartan potassium and Amlodipine, a potent anti-hypertensive agents in pure form and in solid dosage forms was developed in the present study. The linear regression equations for Losartan potassium was Abs=0.09xConc. (in μg/mL) and Amlodipine was Abs=0.015xConc. (in μg/mL) measured at 206 nm and 360 nm respectively. The results of analysis were treated statistically, as per ICH guidelines for validation of analytical procedures, and by recovery studies.
Authors and Affiliations
K. Kaveri , C. Saravanan , Tamizh Mozhi
Keywords
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