Simvastatin-induced rhabdomyolysis: a case study on clinical-decision making based on the evidence-based medicine approach
Journal Title: Archives of Medical Science - Year 2007, Vol 3, Issue 3
Abstract
A case of a woman diagnosed to have rhabdomyolysis is presented. It was attributed to simvastatin she had been receiving for 1 year. Based on pathogenesis and medical examination, the diagnosis of statin-induced rhabdomyolysis was made. Simvastatin was discontinued with concomitant clinical improvement followed by serum creatine kinase decrease. Future course of therapy was decided after reviewing the literature using evidence-based medicine tools. The purpose of this case report is to share our experience so that physicians are reminded of the potential of rhabdomyolysis related to statin use and illustrate the value of evidence-based medicine in clinical practice.
Authors and Affiliations
Konstantinos Koskinas, Thrasyvoulos Tzellos, Kyriakos Gougoulias, Georgios Gougoulias, Christos Papakonstantinou, Dimitrios Kouvelas
Keywords
Related Articles
- EP ID EP91288
- DOI -
- Views 155
- Downloads 0
Current advances in statin treatment: from molecular mechanisms to clinical practice
Highly elevated levels of the antigen Ca-125 associated with inflammatory abdominal masses
CA-125 is well known as an ovarian cancer marker. Various studies have noted it’s growth in benign gynecologic conditions. A young woman was presented with an abdominal discomfort associated with pelvic masses and a very...
Thyroid neoplasms – errors of the cytological diagnosis
Objectives: the evaluation of the diagnostic value of a cytological examination and its limitations for the diagnosis of thyroid neoplasms. Material and methods: From 1995 to 2004 nine hundred ninety eight patients were...
Enhanced proliferation and differentiation of osteoblasts induced by co-culturing with Schwann cells
The effect of monosodium glutamate on the apoptosis of rat thymocytes and Bcl-2 protein expression
Introduction: Monosodium glutamate (MSG) is the sodium salt of glutamic acid widely spread in modern nutrition. Numerous recent studies have shown the existance of glutamic receptors on different non-neuronal cells, whic...