Six Minute Walk Test: A Tool for Predicting Mortality in Chronic Pulmonary Diseases
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 4
Abstract
Introduction: Six Minute Walk Test (6MWT) is a simple test used to measure exercise capacity in Chronic Pulmonary Diseases (CPDs). Decreased exercise capacity significantly affects the quality of life. The 6MWT is a known tool to measure exercise capacity and quality of life in CPD. However, the role of change in follow up Six Minute Walk Distance (6MWD) in assessing mortality and its correlation with known prognostic factors haven’t been tested to the best of our knowledge. Aim: To study the correlation of change in 6MWD with change in spirometry and to study the role of 6MWD in predicting mortality in CPD. Settings and Design: Prospective cohort study. Materials and Methods: A total of 139 CPD patients were grouped into obstructive, restrictive and post Tuberculosis (TB) sequelae. Optimized treatment was given and they were followed up regularly. Spirometry and 6MWT was done at the beginning and after one year. Mean decline in FEV1, FVC was correlated with mean decline in 6MWD. Statistical Analysis: With STATA 13.1 correlation between 6MWT and spirometric values were done using Wilcoxon signed rank test. Predictors of mortality were studied using multivariate analysis. Results: Overall mean decline in 6MWD was 16.07 m/year. There was no correlation between mean change in 6MWD and change in FEV1, FVC, and FEV1/FVC. On multivariate analysis, 6MWD was the better predictor of mortality than FEV1 (p<0.001), FVC (p<0.001). At cut off value of 240 meters, sensitivity and specificity of 6MWT in predicting mortality was 71.05% and 81.94% respectively. Conclusion: The 6MWD changes independently and has no correlation with change in spirometry, it is an independent predictor of mortality in CPD.
Authors and Affiliations
MP Swathi Karanth, Nilkanth Tukaram Awad
Keywords
Related Articles
- EP ID EP337930
- DOI 10.7860/JCDR/2017/24707.9723
- Views 120
- Downloads 0
Effectiveness of Tranexamic Acid for Reducing Postpartum Blood Loss in the First Two Hours after Vaginal Delivery: A Randomised Controlled Trial
ABSTRACT Introduction: Postpartum Haemorrhage (PPH) is the leading direct cause of maternal death worldwide, especially in developing countries. Fibrinolysis is an important process in bleeding during the third stage of...
Intraoral Styloidectomy in Eagle’s Syndrome-A Risky and Infrequently Performed Approach
Abstract Eagle’s syndrome is a symptomatic anomaly due to elongation of styloid process or calcification of stylohyoid ligament manifesting as a pain in cervicofacial region. The present report is of a 45-year-old female...
Primary Ewing’s Sarcoma of Adrenal Gland-A Rare Case
ABSTRACT Ewing’s Sarcoma (ES) or Primitive Neuro-Ectodermal Tumour (PNET) typically occurs in long or flat bones, the chest wall, extra-skeletal soft tissue, and rarely in solid organs. Incidence of urological ES is unco...
Estimation of DMFT, Salivary Streptococcus Mutans Count, Flow Rate, Ph, and Salivary Total Calcium Content in Pregnant and Non-Pregnant Women: A Prospective Study
Introduction: Pregnancy, a period from conception till birth, causes changes in the functioning of the human body as a whole and specifically in the oral cavity that may favour the emergence of dental caries. Many studie...
Neurodynamic Technique for Functional Ankle Instability: A Case Report
ABSTRACT Athletes who encounter repeated Functional Ankle Instability (FAI), exhibit excessive foot inversion during the various phases of gait than non-injured ankle. In gait, heel strike to toe off inversion ankle move...