Skin Diseases in Human Immunodeficiency Virus infected children in the era of Highly Active Antiretroviral Therapy: Epidemiological and Clinical Profile in Pediatric Department of Cotonou, Benin
Journal Title: Journal of Clinical and Investigative Dermatology - Year 2017, Vol 5, Issue 2
Abstract
Aim: To determine the epidemiological and clinical profile of skindiseases in HIV-infected children followed in Pediatric Department atthe University Hospital of Cotonou, Benin. Methods: A 6-month transversal and descriptive study was carriedout and included HIV-infected children aged 6 weeks to 15 years, onor no on antiretroviral therapy, followed since 2002 and who weresuffering of skin disease. Data collected were analyzed with Epi Info6 and SPSS 16. Results:From the 187 children, 61% (114) had at least a skin disorder. The sex ratio M/F was 0.9 and the mean age was 8 years ± 3.8 years. We diagnosed 240 cutaneous diseases parted into infectious 55 cases, 22.9%) and non-infectious (185 cases, 77.1%). At least two skin diseases were observed in 97.4% of children. The 240 skin diseases were distributed according to diagnostic and prognostic interest into common (65.5%), opportunistic (26.6%) and iatrogenic (7.9%). Immuno-depression was absent or insignificant (CD4≥350 / ml) in 82.5% of children and moderate to severe (CD4 < 350/ ml) in 17.5%. Antiretroviral therapy was used in 75.4% of children Conclusion: Highly Active AntiRetroviral Therapies (HAART) have reduced the occurrence of opportunistic dermatosis more than the overall frequency and multiple character of skin diseases in HIVinfected infants in the University Hospital of Cotonou.
Authors and Affiliations
Hugues Adegbidi
Keywords
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- EP ID EP246743
- DOI 10.13188/2373-1044.1000047
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