Sleep disorders in diabetes mellitus type 1 depending on glycemia daily monitoring and achievement of glycemia target levels
Journal Title: Міжнародний ендокринологічний журнал - Year 2017, Vol 13, Issue 3
Abstract
Background. Sleep disorders occur in more than 50 % of the population of developed countries. Changes both in the structure and duration of sleep impact the somatic state of patients. The role of sleep is significant for the regulation of various body functions, hormone secretion, metabolic processes, and glucose homeostasis. The purpose of the study was to access sleep parameters and respiratory events of sleep depending on glycemia level during sleep for patients with type 1 diabetes mellitus. Materials and methods. The study involved 57 patients with type 1 diabetes. Depending on glycemia level during sleep all patients were divided into 3 groups: group 1 (n = 14) included the patients with sleeping glucose less than 3.9 mmol/l; group 2 (n = 25) included the patients with glycemic value 3.9–6.9 mmol/l; group 3 (n = 18) — 7.0–10.0 mmol/l. Glycated hemoglobin, daily monitoring of glycemia, polysomnography were determined in all patients. Results. The study found insufficient duration of total sleep time, a lack of slow sleep stages, more pronounced in patients with decompensation and nocturnal hypoglycemia regardless of diabetes compensation and sleeping hypoglycemia presence. Obstructive sleep apnea is more common in patients with sleeping hypoglycemia, the average duration of this apnea increases with a decrease in the mean value of glycemia on the day before bedtime. Conclusions. The revealed disturbances in sleep structure and the peculiarities of respiration in a sleep with type 1 diabetes can be one of the reasons for the decline in the quality of life of patients with type 1 diabetes.
Authors and Affiliations
T. V. Mokhort, I. P. Darashkevich
Blood level of thyroid-stimulating hormone as a basic diagnostic marker and criterion of success in the treatment of thyroid diseases
In this article, the information is generalized on the aspects of early diagnostics of thyrois disorders. The value of thyroid-stimulating hormone is underlined as a basic test for determination of the thyroid functional...
The Meaning of Using «The Quality of Life Assessment of Growth Hormone Deficiency in Adults» Questionnaire in Patients with Non-Functional Pituitary Adenomas and Various Tumors of Chiasmosellar Area in Pre- and Postoperative Period
The authors have examined 136 patients with growth hormone deficiency (GHD) of various origins (pituitary tumors and ischemic heart disease — comparison group). The investigation of the quality of life on the basis of GH...
Comparative analysis of the activity of cells of innate immunity in patients with benign and malignant thyroid diseases after radioiodine therapy
Background. The effects of radioiodine therapy (RIT) on the cytotoxic activity of NK cells and the metabolic activity of neutrophils (NPs) were studied in patients with toxic goiter (TG) and differentiated thyroid carcin...
Hypothalamic Syndrome
No abstract
The Influence of Metabolic Disorders on Clinical Manifestations of Osteoarthritis and the Method for Predicting Its Course
The objective of the research: to study the impact of metabolic syndrome parameters on the clinical signs of osteoarthritis and to develop the method for predicting osteoarthritis severity based on components of the meta...