Sleep Pattern and Sleep Quality Observed With Tab. Diazepam and Tab. Alprazolam in Patients Treated For Insomnia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Background: The duration and pattern of sleep varies considerably among individuals. Insomnia is characterised by acute or chronic inability to initiate or maintain sleep adequately at night (1). Benzodiazepinereceptor agonists are the most effective and well-tolerated class of medications for insomnia. While there are significant differences among different BZDs, in general, they hasten onset of sleep, reduce intermittent awakening and increase total sleep time. The likely hood of rebound insomnia and tolerance can be minimized by short durations of treatment, intermittent use, or gradual tapering of the dose. Aim/ Objective: To observe the effects of Tab. Diazepam and Tab. Alprazolam on Sleep pattern and sleep quality in patients with insomnia Materials and Methods: Patients who are on T. Diazepam(5-10mg) or T. Alprazolam (0.5-2mg) were assessed for sleep pattern at baseline, at 15 days and at the end of one month. Quality of sleep was evaluated using pittsburgh sleep quality index scale which includes subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, daytime dysfunction. Results and Conclusion: The results of our study reveal that there was a significant difference in sleep pattern and quality of sleep at first follow-up and was consistent till the last follow-up (at the end of one month). It was observed that there was improvement in the primary disease. So, the final score of the sleep pattern parameters is because of the resultant activity of direct drug action and improvement in the underlying disease.
Authors and Affiliations
Dr. K. Thamayanthi, Dr. Vasanthira
Keywords
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