Small cell neuroendocrine carcinoma: A rare second primary malignancy after treatment of nasopharyngeal carcinoma
Journal Title: Romanian Journal of Rhinology - Year 2018, Vol 8, Issue 31
Abstract
Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.
Authors and Affiliations
Krishnamoorthy Madhusudhan, Nor Eyzawiah binti Hassan, Norasnieda binti Md Shukri, Shahrul bin Hitam, Ikmal Hisyam bin Bakrin
Keywords
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- EP ID EP374713
- DOI 10.2478/rjr-2018-0021
- Views 78
- Downloads 0
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