Abstract

Introduction: Smoking is said to be one of the most important cause of mortality. The active substances in cigarettes are administered by burning the leaves and inhaling the vaporized gas. The effects of smoking on human health are serious. With this view present work was planned to study effects of smoking over various haematological parameters in young healthy adults. Material & method: The present study work was conducted in physiology department. We included 70 healthy male subjects between the age group of 20-35 years from MNRMC and Hospital, Sangareddy, out of which 35 were smokers and 35 were non-smokers. Subjects were from staff members, residents and patients from routine OPD. Prior informed written consent was obtained after explaining the procedure and purpose of study tests. The Total Leucocyte Count (TLC) and the Differential Leucocyte Count (DLC) was done by coulter machine automated record . Results: This study showed a significant increase in the TLC from a mean value of 7442/cu.mm in non-smokers to about 8640/cu.mm in smokers (P< 0.01 & Z >2) and an increase in the lymphocyte count in smokers (P< 0.01 & Z >2) as compared to non-smokers. Conclusion: From present study it may be concluded that smoking has a direct effect over haematological parameters.

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