Smoking is a Strong Independent Predictor of Acute Coronary Syndrome Among Patients with Coronary Artery Ectasia
Journal Title: Istanbul Medical Journal - Year 2020, Vol 21, Issue 2
Abstract
Introduction: The independent relationship between smoking and Acute Coronary syndrome (ACS), among other risk factors, was investigated in patients with ectasic coronary arteries. Methods: Between June 2015 and August 2018, 10.320 coronary angiography processes performed in our clinic were analyzed retrospectively. Coronary artery ectasia (CAE) was defined as the enlargement of a coronary artery to 1.5 times or more than that of the local or adjacent normal coronary artery segment. Patients were divided into two groups with (group 1) and without ACS (group 2). The two groups were compared in terms of demographic characteristics, laboratory findings and major risk factors such as hypertension, diabetes mellitus (DM) and smoking. Multivariate logistic regression analysis was used to evaluate independent predictors of ACS in patients with CAE. Results: There were 189 (1.8%) patients with CAE and 143 (76%) of them were male. Of the patients, 107 (57%) were smoking, 106 (56%) had hypertension and 43 (22%) had DM. One hundred two (54%) of the patients presented with ACS. There was no significant difference between the groups in terms of hypertension, DM and basic laboratory characteristics. Smoking rate was significantly higher in the ACS group (66% and 34%, p=0.001). In multivariate logistic regression analysis, when hypertension, DM, age, gender and smoking were evaluated together, smoking was strongly predictive of ACS in patients with ectasic coronary artery [odds ratio: 2.34, (95% confidence interval), 1.093-4.983, p=0.028]. Conclusion: When the factors that play an important role in the etiology of ACS are evaluated together in patients with CAE, smoking predicts ACS strongly and independently.
Authors and Affiliations
Ahmet Gürdal, Serhat Sığırcı, Kadriye Orta Kılıçkesmez
Keywords
Related Articles
- EP ID EP685066
- DOI 10.4274/imj.galenos.2020.40325
- Views 151
- Downloads 0
Short- and Mid-term Effects of Acute Coronary Syndromes on Smoking Behaviour, Factors Affecting Smoking Status and the Family Physicians’ Role After Discharge
Introduction: Cigarette smoking is one of the most important preventable risk factors for atherosclerotic diseases. This study aims to assess the smoking behaviour after acute coronary syndrome (ACS) and aims to delineat...
The Outcomes of Cataract Surgery in Small and Normal Pupillary Eyes with Pseudoexfoliation
Introduction: To evaluate the outcomes of cataract surgery and anterior chamber parameters in pseudoexfoliation cases in our clinic. Methods: The patients, who were admitted to our clinic between 01.03.2016 and 01.04.20...
The Relationship between Coronary Thrombus Burden and Monocyte to High-Density Lipoprotein Cholesterol Ratio in Patients with Acute Non-ST Elevation Myocardial Infarction
Introduction: Non-ST-segment elevation myocardial infarction (NSTEMI) is a condition that constitutes a large part of acute coronary syndromes and has a high mortality rate with diffuse vascular disease. The aim of this...
Clinical Uses of Lactate and Lactate Clearance in Carbon Monoxide Poisoning
Introduction: This study aimed to investigate lactate and lactate clearance and to determine the feasibility of the use of lactate clearance for assessing treatment efficacy in carbon monoxide (CO) poisoning. Methods: A...
The Effects of Low Dose Zinc Supplementation on the Development of New Bone in Rabbits
Introduction: Zinc (Zn) is an essential element for the healthy bone metabolism. It promotes bone formation by stimulating the proliferation and differentiation of osteoblasts, and increases the stimulation of osteoblast...