Solubility and Bioavailability Enhancement of Lurasidone Hydrochloride by SMEDDS
Journal Title: Scholars Academic Journal of Pharmacy - Year 2018, Vol 7, Issue 10
Abstract
The purpose of the present study is to prepare SMEDDS of Lurasidone Hydrochloride. The SMEDDS were prepared by using Propylene glycol dicaprate as oil phase and TPGS and TBCP were selected as emulsifiers, the formed SMEDDS were evaluated for different test. Based on the invitro drug release studies it is confirmed that the increase in the dissolution profile of the SMEDDS when compared to the pure API, which directly implies that increase in the bioavailability of the Lurasidone Hydrochloride.
Authors and Affiliations
R. Shyamsunder, B. Kusum
Keywords
Related Articles
- EP ID EP488612
- DOI -
- Views 106
- Downloads 0
Prospective Study on the Value of Continuous Spinal Anaesthesia in the Case of Femoral Neck among Elderly. 5 Years Chu Dantec
Continuous spinal anesthesia (CSA) is an easy spinal anesthesia technical achievement and without major complication. For this reason we proposed this prospective study from January 2008 to December 2012 about the elderl...
Study on Participatory Learning among MBBS Students in a Medical College of West Bengal, India
Teacher oriented teaching in medical education is still predominantly going on throughout the world including India. Active participation of students is rare or unknown. In these situations, an attempt can be taken as a...
Study on Prevalence of Anaemia among School Children in a Rural Community Setup
Anaemia is one of the important public health problem, which affects the world’s population widely. Among all types of anaemia, iron deficiency anaemia is commonly seen in people of developing countries. The prevalence...
In-vivo Evaluation of Antidiarrhoeal Activity of Ethanolic Extract of Uraria lagopoides (L.)
Uraria lagopoides (L.) (Papilionaceae), a trailing perennial herb locally known as ‘Prisniparni’ finds use as a remedy for several ailments. The purpose of the present study was to evaluate scientifically the anti-diarrh...
A Pharmacognostic and pharmacological overview on Woodfordia fruticosa Kurz.
Woodfordia fruticosa is locally known as Dhawai, belonging to the Lythraceae family. Woodfordia fruticosa is an important medicinal plant of tropical and subtropical India. It has wide range of medicinal and pharmacologi...