Some aspects of prevention of postoperative relapse in patients with nodular forms of goiter

Abstract

Background. Annual prevalence of nodular forms of goiter leads to an increase in the number of surgeries, and therefore, to an increase of postoperative complications. According to different authors, from 3 to 80 % of patients suffering from nodular forms of goiter are operated in case of relapse. This wide range can be caused by the lack of a unified monitoring system, prediction and prevention of relapses during postoperative period. The purpose of the study: to assess the prognostic possibilities of the developed scale to predict the risk of nodular goiter relapse. Materials and methods. 100 case histories of patients suffering from nodular forms of goiter was the material for retrospective study. The main group included 40 persons operated for the second time on goiter relapse; comparison group included 60 persons without relapse. Eighty patients with different forms of goiter became a clinical material for prospective study. The main group consisted of 40 patients with nodular goiter. To choose the volume of surgery in this group, the relapse risk prognostic scale concerning nodular form of goiter was used. The comparison group included 40 patients who underwent surgery without the use of the scale. Results. The retrospective analysis conducted has drawn our attention to the fact that in 80 % of patients with relapse of goiter, the first surgery was sparing, while in 90 % of them, radical surgical would be reasonable. Hemi- or thyroidectomy were performed in 60 % of patients without relapses, while only 45 % of them required such surgery. Prospective study during observation has found that two patients from the first group and 12 patients from the second group had relapses of the disease. Conclusions. Therefore, the relapse risk prognostic scale concerning nodular forms of goiter is an effective method to prevent their relapses.

Authors and Affiliations

N. P. Tkachuk, V. V. Bilookyi, Ya. V. Gyrla

Keywords

Related Articles

Influence of Distribution of Type I Deiodinase Gene Polymorphism on Indices of Thyroid Homeostasis in Patients with Chronic Hepatitis and Nonviral Liver Cirrhosis

The features of thyroid homeostasis in patients with chronic diffuse liver diseases, depending on the A/C polymorphism in DIO1 gene, have been studied. The dependence of indicators of thyroid homeostasis in patients with...

Pathomorphosis of main tyropathies (review of literature and own observations)

The article presents the data of literature review and own observations on the problem of pathomorphosis of the main thyroid diseases under the influence of ecological, radiation, age, hormonal and medical and preventive...

Differential Diagnosis of Primary and Secondary Hyperparathyroidism Caused by Vitamin D Deficiency

Causes of secondary increase of parathyroid hormone, especially vitamin D deficiency, can significantly interfere with the diagnosis of hyperparathyroidism. The most difficult situation occurs when moderate increase in p...

The Syndromic Characteristic of Hereditary Endocrine Pathology

The review considers the brief clinical characteristic of separate syndromes of endocrine pathology, which are based on hereditary factors. Ro define nosological forms there is given OMІM according to the existing classi...

Download PDF file
  • EP ID EP264341
  • DOI 10.22141/2224-0721.13.8.2017.119266
  • Views 55
  • Downloads 0

How To Cite

N. P. Tkachuk, V. V. Bilookyi, Ya. V. Gyrla (2017). Some aspects of prevention of postoperative relapse in patients with nodular forms of goiter. Міжнародний ендокринологічний журнал, 13(8), 536-540. https://europub.co.uk/articles/-A-264341