Some Objectivity to the Ethical Aspects in Conduct of Clinical Research in Vulnerable Population
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 2
Abstract
ABSTRACT Vulnerable population is one of the important parts of our population which also need to be benefited from the results of clinical research. In view of their limited autonomy it may not be easy to conduct clinical research such as clinical trials in them because of ethical issues. When it is must to conduct clinical trial in this population, along with ethical considerations, some statistical and clinical research issues may also be addressed to give the objectivity to the decision of conducting trials in this population, which is not in a position to convey their acceptance of participating in the trial independently. The paper discusses the issues in vulnerable population through the concepts in clinical research and some objective ethical considerations before arriving at the decision of conducting a clinical trial.
Authors and Affiliations
Atul Juneja, Tulsi Adhikari, M Vishnu Vardhana Rao
Keywords
Related Articles
- EP ID EP579037
- DOI 10.7860/JCDR/2019/38396.12629
- Views 85
- Downloads 0
Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
ABSTRACT Rhabdomyosarcoma (RMS) comprises 3% of all childhood malignancy. Commonly it involves head and neck, extremity and genitourinary systems. Pure primary RMS of breast is a rare malignacy. Here, we present a case o...
Defusing a Time Bomb – Embolization of a Uterine Arteriovenous Malformation with Venous Aneurysms
Uterine Arteriovenous Malformation (AVM) is a rare disease and is usually an acquired disorder which can remain asymptomatic or cause life-threatening bleeding. Prompt diagnosis and management in the appropriate clinical...
Effect of Phytonutrient Rich Juice Blends on Antioxidant Status and Lipid Profile in Young Adults: A Randomised Trial
ABSTRACT Introduction: Phytonutrients like polyphenols, carotenoids, glucosinolates and phytoestrogens may not be as essential as micronutrients. But, these have been useful to prevent disease and keep the fitness of th...
A Comprehensive Approach Towards Quality and Safety in Diagnostic Imaging Services: Our Experience at a Rural Tertiary Health Care Center
Introduction: An organization’s transformation from implementation of small, distinct Quality Improvement (QI) efforts to complete incorporation of Quality Improvement Program (QIP) into its culture occurs through a proc...
Digging Deeper into the Patello – Femoral Joint: Patello – Femoral Composite - A New Dimension for Overstuffing of Patello – Femoral Joint
Introduction: Patello–femoral complications are the most common complications in postoperative Total Knee Arthroplasty (TKA) patients especially overstuffing of Patello – Femoral Joint (PFJ). So, to study the effects of...