Some Oxidative Stress Markers in Pregnant Anemic Woman
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Anemia is common disease during pregnancy which is known to promote oxidative stress due to insufficient tissue oxygen supply leading to increased free radical generation and very low level of circulating red blood cells and mobile free radical scavengers which protect the tissues from reactive oxygen species (ROS) mediated damage. In aerobic organisms, free radicals or reactive Oxygen Species (ROS) are produced by normal cellular metabolism or by endogenous sources. These species can cause damage to all biomolecules such as poly-unsaturated fatty acids, DNA and proteins. Malondialdehyde (MDA) is a product of lipid peroxidation of polyunsaturated fatty acids. We have determined the serum MDA, serum uric acid and erythrocyte SOD in pregnant anemic women and pregnant healthy woman (control). We found significantly increased MDA and uric acid significantly decreased erythrocyte SOD in pregnant anemic women as compared to control. This may indicate increased oxidative stress in pregnant anemic woman.
Authors and Affiliations
Dr K. N. Pujari
Keywords
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