SONOLOGICAL EVALUATION OF SOLITARY THYROID NODULES TO PREDICT BENIGN OR MALIGNANT NATURE: A STUDY IN A RURAL TERTIARY CARE HOSPITAL IN SOUTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2014, Vol 3, Issue 9
Abstract
The purpose of this study was to assess the diagnostic accuracy of high frequency Ultrasonography to differentiate the benign and malignant thyroid nodules and to correlate the sonological findings with cytopathological diagnosis. Individual sonological criteria to indicate the malignant nature of a nodule are discussed. [b]MATERIALS AND METHODS:[/b] This was a retrospective study done between January, 2012 and November, 2013 in the Department of Radio-diagnosis at Maharajah’s Institute of Medical Sciences, Nellimerla, Andhra Pradesh. A total of 180 patients with solitary nodule proved on ultrasonography, followed by ultrasound guided fine needle aspiration (FNA) were included in our study. The sonological characteristics of nodules studied were size, shape, margins, echogenicity, calcification, internal composition, presence or absence of peripheral hallow and vascularity pattern. The results were compared to cytopathological findings. [b]RESULTS:[/b] Among the 180 nodules examined, 135 nodules (75%) were proved to be benign and 45 nodules (25%) were proved to be malignant. Patients belonging to all age groups were seen with a clear female preponderance. [b]CONCLUSION: [/b]High frequency ultrasound is of great value in characterization and differentiation of benign and malignant nodules. It can be successfully used as a guideline to select the patients for fine needle aspiration, in case of suspicious malignant nodule. The sonological criteria favoring malignancy are irregular margins, hypoechogenicity, taller than wide shape, microcalcifications and internal vascularity. The combination of multiple parameters increases the predictive value of ultrasonography.
Authors and Affiliations
Madhavi Chamarthi, Abhilash S, Kejriwal G. S
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