Speciation and antibiotic resistance pattern of Acinetobacter species in a tertiary care hospital in Uttarakhand
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 4
Abstract
Acinetobacter species are Gram negative nonfermentative bacteria that have now emerged as important nosocomial pathogens involved in outbreaks of hospital infections.They are considered as opportunistic pathogens that readily colonize patients with compromised host defenses especially in intensive care units (ICUs), neonatal units, and surgical wards. The current study was conducted to type the Acinetobacter isolates obtained from various sources by a simplified phenotypic identification scheme and also to determine their antimicrobial susceptibility. Specimens like blood, CSF, endotracheal aspirate, urine, sputum, pus, bronchoalveolar lavage, HVS and body fluids were processed by standard methods and the antibiotic-sensitivity was performed by Kirby-Bauer disk diffusion technique as per Clinical and Laboratory Standards Institute guidelines (CLSI). The study was conducted in a tertiary care hospital for a period of 6 months (July 2013 – Dec 2013) in which out of a total of 1272 culture positive specimens, 53 Acinetobacter isolates were obtained from various specimens. Speciation was done in which predominance of A. baumannii( 90.6%) was seen while A. lwoffii and A. haemolyticus showed an isolation rate of 5.7% and 3.8% respectively. High levels of resistance were seen for Ampicillin –Sulbactam (96%), Ampicillin (94%), Aztreonam (94%), Cefuroxime (92%), ceftazidime (91%). The p-value was found to be statistically significant for all the above mentioned antibiotics except for Polymyxin B for which 100% sensitivity was recorded. Clinical co-relation must be under taken to exclude commensal contaminants, before considering it to be a pathogen and prescribing antibiotics to the patient.
Authors and Affiliations
Raina Dimple| Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, India, Sharma Nupur| Department of Microbiology, AIIMS , Delhi, India, Mahawal B. S. | Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, India, Khanduri Ankit| Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Indiac, Pandita Ajay| Department of Community Medicine Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, IndiaCorresponding email: dr.dimpleraina@gmail.com
Keywords
Related Articles
- EP ID EP11645
- DOI -
- Views 267
- Downloads 11
Development of Verbal Expressive Skills Management Programme (VESMP) for Patients with Broca’s Aphasia
Introduction: Disorders of communication, including aphasia (mainly post stroke) caused by the left hemisphere brain damage, is a major community health issue. The prevalence of aphasia after stroke is 25% in Pakistan i...
Community empowering models to gout management: A study among Indonesian cadres and elderly
The incidence of physical mobility impairment and pain that caused by excess of uric acid in the joints is on the increase. Uric acid is a product of purine metabolism that tends to occur in the elderly but now is commo...
Association ofMitochondrial T16519C polymorphism with Coronary Artery Disease (CAD) in Iranian patients underwent coronary angiography
Early diagnosis, before manifestation of symptoms or identifying susceptibility to diseases can reduce the severity and prevalence and may even control or inhibit the disease progression. Now the relationship between th...
Economic evaluation (quantitative) for Mung bean (Vigna radiata) production in the Kamin Region, Sadat Shahr, Fars province
Although one of the biggest disadvantages of an economic evaluation, is volatility of price and instability of economic conditions, But for land use planning, economic considerations play a key role in land use and maki...
COMPARISON OF ENDOSCOPIC SINUS SURGERY AND ANTRAL WASH OUT IN THE MANAGEMENT OF SUBACUTE AND CHRONIC MAXILLARY SINUSITIS
Introduction: Sub acute and chronic maxillary sinusitis is commonly encountered in day to day ENT practice. Here we compare the management options available in the treatment of these two conditions. Methodology: Endosc...