Speciation and antibiotic resistance pattern of Acinetobacter species in a tertiary care hospital in Uttarakhand
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 4
Abstract
Acinetobacter species are Gram negative nonfermentative bacteria that have now emerged as important nosocomial pathogens involved in outbreaks of hospital infections.They are considered as opportunistic pathogens that readily colonize patients with compromised host defenses especially in intensive care units (ICUs), neonatal units, and surgical wards. The current study was conducted to type the Acinetobacter isolates obtained from various sources by a simplified phenotypic identification scheme and also to determine their antimicrobial susceptibility. Specimens like blood, CSF, endotracheal aspirate, urine, sputum, pus, bronchoalveolar lavage, HVS and body fluids were processed by standard methods and the antibiotic-sensitivity was performed by Kirby-Bauer disk diffusion technique as per Clinical and Laboratory Standards Institute guidelines (CLSI). The study was conducted in a tertiary care hospital for a period of 6 months (July 2013 – Dec 2013) in which out of a total of 1272 culture positive specimens, 53 Acinetobacter isolates were obtained from various specimens. Speciation was done in which predominance of A. baumannii( 90.6%) was seen while A. lwoffii and A. haemolyticus showed an isolation rate of 5.7% and 3.8% respectively. High levels of resistance were seen for Ampicillin –Sulbactam (96%), Ampicillin (94%), Aztreonam (94%), Cefuroxime (92%), ceftazidime (91%). The p-value was found to be statistically significant for all the above mentioned antibiotics except for Polymyxin B for which 100% sensitivity was recorded. Clinical co-relation must be under taken to exclude commensal contaminants, before considering it to be a pathogen and prescribing antibiotics to the patient.
Authors and Affiliations
Raina Dimple| Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, India, Sharma Nupur| Department of Microbiology, AIIMS , Delhi, India, Mahawal B. S. | Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, India, Khanduri Ankit| Department of Microbiology Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Indiac, Pandita Ajay| Department of Community Medicine Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, IndiaCorresponding email: dr.dimpleraina@gmail.com
Keywords
Related Articles
- EP ID EP11645
- DOI -
- Views 234
- Downloads 11
RARE PRESENTATION OF RUPTURED RUDIMENTARY HORN PREGNANCY
It is a rare occurrence for the rudimentary horn of uterus to harbour a pregnancy and the usual outcome is devastating leading to a spontaneous rupture in second trimester with the patient presenting in shock with mas...
CLINICO-BACTERIOLOGICAL PROFILE OF DIABETIC FOOT ULCER AMONG THE PATIENTS ATTENDING RURAL TERTIARY HEALTH CARE CENTRE
Background: Worldwide diabetic foot is a major medical problem leading to disability and economic instability to family and country. Objectives: To assess the clinical and bacteriological profile of diabetic foot ulcer...
The impact of Ecotourism on quality of life of elderly orientation
This study aimed to assess the impact of ecotourism on quality of life and the life orientation of the elderly people. The method was a quasi-experimental study with pretest-posttest control group, respectively. 32 reti...
Association between sodium bicarbonate consumption and human health: A systematic review
Sodium bicarbonate or baking soda is a chemical compound dissolved in water which is widely used as an additive in foods and mineral water and as a medicine. In Iran, due to the introduction of harmful effects of this c...
Two cases of retained ureteral stents presenting with breakage and encrustations
Ureteral stents (Double J stents) have become an integral part of today’s urologic practice. But complications like stent migration, encrustation, stone formation and fragmentation have been found when these stents ar...