Speciation and antifungal susceptibility profile of candida isolates from urine samples in a tertiary care hospital
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 6
Abstract
Background: Candiduria is one of the most common symptoms of urinary tract infections caused by several species of Candida. Several antifungal drugs are available to treat such candida infections. During the last decade, resistance to antifungals especially in non-albicans species has increased. Objectives: The present study aimed to evaluate the speciation and antifungal susceptibility profile of Candida isolates from urine samples. Materials and Methods: A total of 100 Candida spp. isolated from urine samples were included in the study. Speciation of Candida was done by conventional methods and colony color on CHROM agar. Antifungal susceptibility testing of the isolates was performed by disc diffusion method on Glucose Methylene Mueller - Hinton agar (GM-MH) Results: Candiduria was more common in females. In both the sexes maximum patients belong to age group 51-60 years. Urinary catheterization followed by the use of broad spectrum antibiotics and diabetes mellitus were the major risks for the development of candiduria. Out of 100 isolates, 36(36%) were C. albicans whereas 64 (64%) belonged to Non albicans Candida (NAC) spp. Among NAC spp. C. tropicalis was the major isolate. Candida species showed maximum sensitivity to Amphotericin B 95%, followed by Ketoconazole 69%, Conclusions: Candiduria is becoming an important nosocomial infection. Incidence of non Candida albicans was more than Candida albicans. NAC species are more resistance to antifungal as compared to C albicans
Authors and Affiliations
Sushma Atal, Ramesh Kumar Mishra, Rakesh Kumar Maheshwari
Keywords
Related Articles
- EP ID EP586165
- DOI -
- Views 166
- Downloads 0
Assessment of dermatological lesions in HIV reactive patients: A Histopathogical Evaluation
The possibility of adverse drug reaction should always be included in the differential diagnosis of any inflammatory dermatomes in HIV positive patients. Drugs may give rise to variety of histological patterns e.g. lichi...
Functional endoscopic sinus surgery in chronic rhinosinusitis and subjective assessment of its outcome
Rhinosinusitis is a significant health problem which results in large financial burden on society. The study evaluated the prevalence and severity of individual symptoms of chronic rhinosinusitis (CRS) and the impact of...
A study on the significance of neonatal and infantile spinal sonography
Sonography is an ideal, effective, noninvasive tool for evaluation of the spinal cord in neonatal and early infantile age groups owing to lack of ossification of the posterior elements of spine. Understanding normal anat...
A comprehensive review on Aphthous ulcers of oral cavity
Recurrent aphthous stomatitis, also commonly referred to as aphthous ulcers, can be defined as an immensely customary excruciating condition which affects variegated areas of the oral cavity. It is common complaint of pa...
Comparing vascularization assessed by transvaginal sonography and colour Doppler with pelvic pain and Revised American Society for Reproductive staging in women with endometriosis
Background: Endometriosis is a disease causing severe pelvic pain. Previous data has shown that it has contributed to 15% infertility. Transvaginal Color Doppler is the noninvasive tool to assess ovarian endometrial vasc...