Speciation and antifungal susceptibility profile of candida isolates from urine samples in a tertiary care hospital
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 6
Abstract
Background: Candiduria is one of the most common symptoms of urinary tract infections caused by several species of Candida. Several antifungal drugs are available to treat such candida infections. During the last decade, resistance to antifungals especially in non-albicans species has increased. Objectives: The present study aimed to evaluate the speciation and antifungal susceptibility profile of Candida isolates from urine samples. Materials and Methods: A total of 100 Candida spp. isolated from urine samples were included in the study. Speciation of Candida was done by conventional methods and colony color on CHROM agar. Antifungal susceptibility testing of the isolates was performed by disc diffusion method on Glucose Methylene Mueller - Hinton agar (GM-MH) Results: Candiduria was more common in females. In both the sexes maximum patients belong to age group 51-60 years. Urinary catheterization followed by the use of broad spectrum antibiotics and diabetes mellitus were the major risks for the development of candiduria. Out of 100 isolates, 36(36%) were C. albicans whereas 64 (64%) belonged to Non albicans Candida (NAC) spp. Among NAC spp. C. tropicalis was the major isolate. Candida species showed maximum sensitivity to Amphotericin B 95%, followed by Ketoconazole 69%, Conclusions: Candiduria is becoming an important nosocomial infection. Incidence of non Candida albicans was more than Candida albicans. NAC species are more resistance to antifungal as compared to C albicans
Authors and Affiliations
Sushma Atal, Ramesh Kumar Mishra, Rakesh Kumar Maheshwari
Keywords
Related Articles
- EP ID EP586165
- DOI -
- Views 154
- Downloads 0
Study of foetal and perinatal outcome in subclinical and overt hypothyroid disorders in pregnancy
In India thyroid disorders are in a transition zone from a predominant iodine deficient nation to now an iodine sufficient population. Rate of foetal loss is twice normal, there is increased risk of preterm delivery, 10...
Assessment of risk factors for the four major non-communicable diseases among the catholic university of eastern Africa staff, Langata campus, Nairobi, Kenya
Background: Non-communicable diseases (NCDs) are the leading cause of global disability and premature death. The negative consequences are particularly heavy in developing countries in terms of the impact on health and p...
Study on outcome of administration of aspirin on suxamethonium induced myalgia
This study was planned out to find out the consequences of oral aspirin in decreasing the frequency of post-operative myalgia triggered by supervision of suxamethonium and to relate it with precurarization (with pancuron...
Epidemiology of atopic dermatitis among children in Jazan Region, Saudi Arabia
Little information is available about the prevalence of these diseases in Jazan Region, Saudi Arabia, especially among the children. This study cross-sectional study was designed to identify the prevalence of AD symptoms...
A study on clinical profile of patients with acute ischemic stroke
Introduction: Cerebrovascular disease ranks the first in frequency and importance among all the neurological diseases in adult life. Stroke is the most common cause of death, after heart disease and cancer. Cerebrovascul...